DISCOVERY OF DEATH LIGANDS AGAINST CANCERS


Year of Award:
2012
Award Type:
R33
Project Number:
CA160132
RFA Number:
RFA-CA-12-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
LAM, KIT S
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIFORNIA AT DAVIS
Recently, we have modified the one-bead-one-compound (OBOC) combinatorial library method by adding a known cell adhesion (or cell capturing) ligand to the surface of every bead in the OBOC library. When live cells are incubated with such novel one-bead-tw