APPLICATION OF AN INNOVATIVE TECHNOLOGY TO DEVELOP LOW TOXICITY KINASE INHIBITORS


Year of Award:
2011
Award Type:
R21
Project Number:
CA155568
RFA Number:
RFA-CA-10-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
BIEBERICH, CHARLES J.
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF MARYLAND BALT CO CAMPUS
Kinase inhibition is a viable treatment approach for multiple diseases including cancer, diabetes, and Alzheimer's. Although small molecule inhibitors have occupied center stage in the kinase inhibition arena, challenges with toxicity and emergence of res