Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2022 | R33 | CA272321 | RFA-CA-21-004 | WANG, TZA-HUEI JEFF | JOHNS HOPKINS UNIVERSITY | A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies | Active |
2021 | R21 | CA261734 | CA20-019 | AKSAN, ALPTEKIN | UNIVERSITY OF MINNESOTA | Novel cryopreservation method for stabilization of manufactured therapeutic cells | Active |
2021 | R21 | CA263147 | CA20-017 | BHARGAVA, ROHIT | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN | Spectroscopy Assisted Laser Microdissection | Active |
2020 | R21 | CA240185 | RFA-CA-19-019 | LI, WEI | TEXAS TECH UNIVERSITY | Fractionation And Profiling Of Heterogeneous Circulating Tumor Cells Using A Hyperuniform- Structured Microchip | Active |
2023 | R61 | CA278559 | RFA-CA-22-001 | LU, YUE | UNIVERSITY OF UTAH | Vesicle Epitope Transcript sequencing (VET-seq): Droplet-based Multiomic Profiling Platform for Single Vesicle Analysis | Active |
2022 | R21 | CA261643 | RFA-CA-21-005 | TANG, SINDY KAM-YAN | STANFORD UNIVERSITY | A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy | Active |
2021 | R33 | CA252158 | CA20-018 | ZENG, YONG | UNIVERSITY OF FLORIDA | Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles | Active |
2020 | R21 | CA247638 | RFA-CA-19-019 | LIANG, FU-SEN | CASE WESTERN RESERVE UNIVERSITY | Spatiotemporal Epitranscriptome Editing Technology | Active |
2021 | R43 | CA261362 | PAR-18-303 | ALLEN, JEFFREY KEITH | TUMORGEN, INC. | Capture and Characterization of Highly Metastatic Cancer Cell Clusters in Transit from Lung Cancer Patient Whole Blood Specimens. | Active |
2023 | R61 | CA278459 | RFA-CA-22-001 | PRATX, GUILLEM | STANFORD UNIVERSITY | A Novel Assay to Individualize Resensitization of Iodine-Refractory Thyroid Cancer | Active |
2021 | R33 | CA256086 | CA20-018 | JIANG, NING JENNY | UNIVERSITY OF PENNSYLVANIA | A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells | Active |
2022 | R21 | CA257942 | RFA-CA-21-003 | GIBBS, SUMMER LYNNE | OREGON HEALTH & SCIENCE UNIVERSITY | A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors | Active |
2021 | R33 | CA256112 | CA20-018 | WEI, WEI | INSTITUTE FOR SYSTEMS BIOLOGY | Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy | Active |
2023 | R61 | CA281795 | RFA-CA-22-001 | CAMPAGNOLA, PAUL J | UNIVERSITY OF WISCONSIN-MADISON | A novel multimodal ECM analysis platform for tumor characterization combining morphological and spectrochemical tissue imaging approaches. | Active |
2021 | R33 | CA261726 | CA20-018 | CHENG, JI-XIN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) | Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy | Active |
2020 | R21 | CA251052 | RFA-CA-19-019 | SHVETS, GENNADY | CORNELL UNIVERSITY | Phenotypic Assay For Drug Discovery And Personalized Medicine Based On Real-time Vibrational Spectroscopy Enhanced By Plasmonic Metasurfaces | Active |
2023 | R33 | CA278510 | RFA-CA-22-004 | DUNCAVAGE, ERIC J | WASHINGTON UNIVERSITY | A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer | Active |
2020 | R21 | CA225493 | RFA-CA-19-019 | TEWARI, MUNEESH | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Highly Specific, Amplification-free, Single-molecule Counting Of Rare Methylated Dna Cancer Biomarkers | Active |
2018 | R43 | CA236097 | PAR-18-303 | LIM, MARK | AMBERGEN, INC | Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues | Active |
2022 | R33 | CA259451 | RFA-CA-21-004 | NAEGLE, KRISTEN M | UNIVERSITY OF VIRGINIA | A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides | Active |
2021 | R21 | CA255979 | CA20-017 | DIDENKO, VLADIMIR V | BAYLOR COLLEGE OF MEDICINE | In situ assay imaging nuclear RNA exosome activity for cancer studies | Active |
2020 | R33 | CA251037 | RFA-CA-19-020 | WANG, SIYUAN | YALE UNIVERSITY | Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer | Active |
2023 | R33 | CA277820 | RFA-CA-22-002 | WEISSLEDER MD PHD, RALPH | MASSACHUSETTS GENERAL HOSPITAL | Bioorthogonal probe development for highly parallel in vivo imaging | Active |
2021 | R21 | CA261737 | CA20-017 | HAINER, SARAH JANE | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN | Active |
2020 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations | Active |
2023 | R33 | CA278393 | RFA-CA-22-002 | VAN GALEN, PETER | BRIGHAM AND WOMEN'S HOSPITAL | Clonal analysis of cancer by mitochondrial DNA barcoding | Active |
2023 | R33 | CA278551 | RFA-CA-22-002 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | Combining Machine Learning and Nanofluidic Technology for The Multiplexed Diagnosis of Pancreatic Adenocarcinoma | Active |
2021 | R21 | CA251027 | CA20-017 | SCHULMAN, REBECCA | JOHNS HOPKINS UNIVERSITY | Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) | Active |
2023 | R33 | CA278544 | RFA-CA-22-004 | LEVENSON, RICHARD M | UNIVERSITY OF CALIFORNIA AT DAVIS | CoreView and FIBI for rapid-onsite evaluation and molecular profiling of core-needle breast biopsies. | Active |
2022 | R21 | CA267012 | CA21-003 | SNYDER, JOSHUA CLAIR | DUKE UNIVERSITY | Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color | Active |
2020 | R33 | CA246448 | RFA-CA-19-020 | HALL, ADAM ROGER | WAKE FOREST UNIVERSITY HEALTH SCIENCES | Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores | Active |
2023 | R61 | CA281807 | RFA-CA-22-001 | HACOHEN, NIR | BROAD INSTITUTE, INC. | Development of methods for highly multiplexed quantification of cancer proteomes using large-scale nanobody libraries | Active |
2022 | R21 | CA272014 | RFA-CA-21-003 | SALIPANTE, STEPHEN J | UNIVERSITY OF WASHINGTON | Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations | Active |
2022 | R21 | CA250999 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Aliquot-level visual indicators of biospecimen exposure to thawed conditions | Active |
2023 | R33 | CA272331 | RFA-CA-22-002 | MURETTA, JOSEPH M | UNIVERSITY OF MINNESOTA | Engineering Protein Modulators of Notch Activation for T-cell immunotherapy | Active |
2022 | R21 | CA257864 | CA21-003 | BOYLE, ALAN P | UNIVERSITY OF MICHIGAN AT ANN ARBOR | High-throughput inverted reporter assay for characterization of silencers and enhancer blockers | Active |
2021 | R21 | CA236665 | RFA-CA-20-019 | SANTORE, MARIA M | UNIVERSITY OF MASSACHUSETTS AMHERST | Paper-based Breastmilk Collection System for Facile, In-Home Use | Active |
2022 | R21 | CA261642 | RFA-CA-21-003 | NABA, ALEXANDRA | UNIVERSITY OF ILLINOIS AT CHICAGO | Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix | Active |
2022 | R21 | CA258008 | CA21-003 | SCARCELLI, GIULIANO | UNIV OF MARYLAND, COLLEGE PARK | Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential | Active |
2021 | R21 | CA247647 | RFA-CA-20-017 | WILSON, GERALD M | UNIVERSITY OF MARYLAND BALTIMORE | Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases | Active |
2022 | R33 | CA267219 | RFA-CA-21-004 | LANDAU, DAN | WEILL MEDICAL COLL OF CORNELL UNIV | Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes | Active |
2022 | R33 | CA267221 | CA21-004 | NORMAN, THOMAS MAXWELL | SLOAN-KETTERING INST CAN RESEARCH | Systematic characterization of cancer variants using single-cell functional genomics | Active |
2021 | R21 | CA250597 | RFA-CA-20-017 | ZHANG, FANGLIANG | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE | Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) | Active |
2000 | R21 | CA083391 | PAR-98-066 | HAMPDEN-SMITH, MARK J | SUPERIOR MICROPOWDERS, LLC | UNIQUE, SMALL PARTICLE PHOSPHOR POWDERS FOR IMUNOASSAYS | Complete |
2002 | R33 | CA088335 | PAR-99-100 | SUTHERLAND, JOHN CLARK | BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB | DNA DAMAGE QUANTITATION BY SINGLE MOLECULE LASER SIZING | Complete |
2005 | R44 | CA101106 | RFA-CA-05-006 | RUSH, JOHN | CELL SIGNALING TECHNOLOGY, INC. | IMMUNOAFFINITY ISOLATION OF PHOSPHOPEPTIDES | Complete |
2008 | R43 | CA132680 | RFA-CA-07-041 | CHAN, DOUG | PROTECH LABORATORIES, INC. | DEVELOPMENT AND APPLICATION OF TECHNOLOGY PLATFORM FOR IDENTIFICATION OF THE HIST | Complete |
2011 | R33 | CA155586 | RFA-CA-10-004 | PORTER, MARC D | UNIVERSITY OF UTAH | ADVANCED DEVELOPMENT OF A MULTIPLEXED SERS-BASED BIOMARKER DETECTION PLATFORM: A | Complete |
2015 | R43 | CA187787 | PAR-13-327 | SELIGMANN, BRUCE E. | BIOSPYDER TECHNOLOGIES, INC. | IN SITU RNA-FISH WITH LOCALIZED PROFILING BY SEQUENCING FROM FFPE | Complete |
2019 | R21 | CA235285 | RFA-CA-18-002 | KENTSIS, ALEX | SLOAN-KETTERING INST CAN RESEARCH | Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics | Complete |