Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2019 | R21 | CA229069 | RFA-CA-18-002 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants | Complete |
2019 | R21 | CA236652 | RFA-CA-18-004 | SINGAMANENI, SRIKANTH | WASHINGTON UNIVERSITY | METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION | Complete |
2019 | R33 | CA225498 | RFA-CA-18-003 | CHEN, SIDI | YALE UNIVERSITY | Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers | Complete |
2019 | R21 | CA236640 | RFA-CA-18-002 | BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories for targeting interstitial fluid pressure | Complete |
2019 | R33 | CA225458 | RFA-CA-18-003 | KETTENBACH, ARMINJA NADINE | DARTMOUTH COLLEGE | Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics | Complete |
2019 | R33 | CA229042 | RFA-CA-18-003 | SCHNECK, JONATHAN P | JOHNS HOPKINS UNIVERSITY | A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells | Complete |
2019 | R21 | CA236594 | RFA-CA-18-002 | GARBER, MANUEL | UNIV OF MASSACHUSETTS MED SCH WORCESTER | A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells | Complete |
2019 | R21 | CA236561 | RFA-CA-18-002 | WEISSLEDER, RALPH | MASSACHUSETTS GENERAL HOSPITAL | Single Circulating Vesicle Analysis for Early Cancer Detection | Complete |
2018 | R43 | CA236142 | PAR-18-303 | SCHOETTLE, LOUIS | GEMNEO BIOSCIENCE, INC. | Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes | Complete |
2018 | R43 | CA236097 | PAR-18-303 | LIM, MARK | AMBERGEN, INC | Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues | Active |
2019 | R43 | CA236177 | PAR-18-303 | KASOJI, SANDEEP | TRIANGLE BIOTECHNOLOGY, INC. | SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples | Complete |
2018 | R43 | CA236101 | PAR-18-303 | LEE, LY JAMES | NANOMATERIAL INNOVATION, LTD | Molecular Beacons in Lipoplex Nanoparticles for Extracellular Vesicles Based Cancer Diagnosis | Complete |
2019 | R43 | CA236103 | PAR-18-303 | KHODAVERDIAN, VARANDT Y. | NUPROBE USA, INC. | Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing | Complete |
2019 | R21 | CA235340 | RFA-CA-18-002 | ZHU, YAZHEN | UNIVERSITY OF CALIFORNIA LOS ANGELES | Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs | Complete |
2019 | R33 | CA235326 | RFA-CA-18-005 | LEI, YUGUO | UNIVERSITY OF NEBRASKA LINCOLN | A Single Conical Tube Device for Precision CAR-T Cells Manufacturing | Complete |
2019 | R21 | CA235305 | RFA-CA-18-002 | WU, YUN | STATE UNIVERSITY OF NEW YORK AT BUFFALO | Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection | Complete |
2019 | R21 | CA235303 | RFA-CA-18-002 | YAMAMOTO, KEITH ROBERT | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer | Complete |
2019 | R33 | CA225549 | RFA-CA-18-003 | TAVANA, HOSSEIN | UNIVERSITY OF AKRON | A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery | Complete |
2019 | R21 | CA235285 | RFA-CA-18-002 | KENTSIS, ALEX | SLOAN-KETTERING INST CAN RESEARCH | Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics | Complete |
2019 | R33 | CA235254 | RFA-CA-18-003 | FIOLKA, RETO PAUL | UT SOUTHWESTERN MEDICAL CENTER | Multiscale microscope for 3D cancer imaging in model organisms and organoids | Complete |
2019 | R21 | CA223727 | RFA-CA-18-002 | HUANG, XIAOHUA | UNIVERSITY OF CALIFORNIA, SAN DIEGO | Technology for measuring telomere length of individual chromosomes of single cancer cells | Complete |
2020 | R43 | CA243757 | PAR-18-303 | ERVIN, ERIC | ELECTRONIC BIOSCIENCES, INC. | N6-Methyl-2-O-Methyladenosine Sequencing | Complete |
2020 | R43 | CA250805 | PAR-18-303 | WANG, SHA | VIVID TECHNOLOGIES | New specific and rapid assay for in situ apoptosis labeling for cancer studies | Complete |
2020 | R33 | CA247739 | RFA-CA-19-020 | MATRIX BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories For Targeting Extracellular Matrix | Active |
2020 | R21 | CA240220 | RFA-CA-19-019 | ALEXANDRAKIS, GEORGIOS | UNIVERSITY OF TEXAS ARLINGTON | Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy | Active |
2020 | R21 | CA247638 | RFA-CA-19-019 | LIANG, FU-SEN | CASE WESTERN RESERVE UNIVERSITY | Spatiotemporal Epitranscriptome Editing Technology | Active |
2020 | R33 | CA236670 | RFA-CA-19-020 | HIGGINSON, DANIEL | SLOAN-KETTERING INST CAN RESEARCH | Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways | Complete |
2020 | R33 | CA236681 | RFA-CA-19-020 | WEI, CHIA-LIN | JACKSON LABORATORY | Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer | Complete |
2020 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations | Active |
2018 | R21 | CA214285 | RFA-CA-17-010 | MAILLOUX, ADAM WILLIAM | H. LEE MOFFITT CANCER CTR & RES INST | Autohistomagnetic Isolation of Tumor-reactive T-cells | Complete |
2018 | R21 | CA229057 | RFA-CA-17-010 | FU, XIAO-AN | UNIVERSITY OF LOUISVILLE | A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath | Complete |
2018 | R21 | CA229044 | RFA-CA-17-010 | ABBOTT, KAREN L | UNIV OF ARKANSAS FOR MED SCIS | Novel platform linking cancer-specific glycosylation with cell signaling outcomes | Complete |
2018 | R21 | CA229037 | RFA-CA-17-012 | GULLEY, MARGARET L | UNIV OF NORTH CAROLINA CHAPEL HILL | EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing | Complete |
2018 | R21 | CA229027 | RFA-CA-17-012 | SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN | WAKE FOREST UNIVERSITY HEALTH SCIENCES | Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids | Complete |
2018 | R33 | CA223947 | RFA-CA-17-011 | BROWN, BRIAN D | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | Pro-Codes: A novel vector and cell barcoding technology | Complete |
2018 | R33 | CA229023 | RFA-CA-17-011 | TEWARI, MUNEESH (contact); WALTER, NILS G | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations | Complete |
2018 | R21 | CA228997 | RFA-CA-17-010 | ROYZEN, MAKSIM | STATE UNIVERSITY OF NEW YORK AT ALBANY | Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies | Complete |
2018 | R33 | CA217702 | RFA-CA-17-013 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Validation and Advanced Development of Albumin Oxidizability as a Marker of Plasma/Serum Integrity | Complete |
2018 | R33 | CA228979 | RFA-CA-17-011 | SCHRUM, ADAM G | UNIVERSITY OF MISSOURI-COLUMBIA | Multiplex matrix ELISA for T cell protein-interaction networks in cancer | Complete |
2018 | R21 | CA228948 | RFA-CA-17-010 | SCHIBEL, ANNA | ELECTRONIC BIOSCIENCES, INC. | Microsatellite Sequencing to Enable Cancer Genotyping | Complete |
2018 | R33 | CA223581 | RFA-CA-17-011 | CHENG, JI-XIN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) | Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level | Complete |
2018 | R33 | CA225863 | RFA-CA-17-011 | LU, JUN | YALE UNIVERSITY | CRISPR-based Enhanced Molecular Chipper Technology for Identifying Functional Noncoding Elements in Cancer | Complete |
2018 | R21 | CA217735 | RFA-CA-17-010 | ENGLER, ADAM JEFFREY | UNIVERSITY OF CALIFORNIA, SAN DIEGO | Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells | Complete |
2018 | R33 | CA225539 | RFA-CA-17-011 | JIANG, NING | UNIVERSITY OF TEXAS, AUSTIN | An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer | Complete |
2018 | R21 | CA225507 | RFA-CA-17-012 | PAULOVICH, AMANDA G | FRED HUTCHINSON CANCER RESEARCH CENTER | Validation of a disposable biospecimen collection system with integral refrigeration for preserving the phosphoproteome | Complete |
2018 | R33 | CA225494 | RFA-CA-17-011 | LIU, YANG | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | High-throughput super-resolution imaging of chromatin structures at different epigenetic states | Complete |
2018 | R21 | CA225474 | RFA-CA-17-010 | MEHTA, ANAND S | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Glyco-typer: an antibody capture glycan imaging methodology | Complete |
2018 | R21 | CA223901 | RFA-CA-17-010 | BRENT, ROGER | FRED HUTCHINSON CANCER RESEARCH CENTER | Precision controllers of mammalian gene expression | Complete |
2018 | R21 | CA223887 | RFA-CA-17-010 | SMITH, LLOYD M | UNIVERSITY OF WISCONSIN-MADISON | Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues | Complete |
2018 | R21 | CA223853 | RFA-CA-17-010 | ROBLES, FRANCISCO E | GEORGIA INSTITUTE OF TECHNOLOGY | Stimulated Raman scattering spectroscopic optical coherence tomography (SRS-SOCT) for label-free molecular imaging of brain tumor pathology | Complete |