Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project #sort ascending RFA # PI/Project Leader Institution Title Status
2019 R21 RFA-CA-18-002 MONTAGNA, CRISTINA ALBERT EINSTEIN COLLEGE OF MEDICINE Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions Complete
2019 R33 RFA-CA-18-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia Complete
2019 R21 RFA-CA-18-004 ANDRES-MARTIN, LAURA NEW YORK STEM CELL FOUNDATION Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections Complete
2019 R33 RFA-CA-18-003 VAN DAM, ROBERT MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research Complete
2019 R21 RFA-CA-18-002 O'NEILL, RACHEL UNIVERSITY OF CONNECTICUT STORRS Development and Utilization of Splice-specific Antibodies Complete
2019 R33 RFA-CA-18-003 DE VLAMINCK, IWIJN CORNELL UNIVERSITY Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer Complete
2019 R21 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Complete
2019 R21 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Complete
2019 R21 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Complete
2019 R43 PAR-18-303 BROWN, MARK T CLAREMONT BIOSOLUTIONS, LLC Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis Complete
2019 R43 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations Complete
2019 R21 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Complete
2019 R33 RFA-CA-18-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models Complete
2019 R21 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Complete
2019 R21 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Complete
2019 R21 RFA-CA-18-004 SINGAMANENI, SRIKANTH WASHINGTON UNIVERSITY METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION Complete
2019 R33 RFA-CA-18-003 CHEN, SIDI YALE UNIVERSITY Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers Complete
2019 R21 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Complete
2019 R33 RFA-CA-18-003 KETTENBACH, ARMINJA NADINE DARTMOUTH COLLEGE Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics Complete
2019 R33 RFA-CA-18-003 SCHNECK, JONATHAN P JOHNS HOPKINS UNIVERSITY A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells Complete
2019 R21 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Complete
2019 R21 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Complete
2018 R43 PAR-18-303 SCHOETTLE, LOUIS GEMNEO BIOSCIENCE, INC. Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes Complete
2018 R43 PAR-18-303 LIM, MARK AMBERGEN, INC Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues Active
2019 R43 PAR-18-303 KASOJI, SANDEEP TRIANGLE BIOTECHNOLOGY, INC. SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples Complete
2018 R43 PAR-18-303 LEE, LY JAMES NANOMATERIAL INNOVATION, LTD Molecular Beacons in Lipoplex Nanoparticles for Extracellular Vesicles Based Cancer Diagnosis Complete
2019 R43 PAR-18-303 KHODAVERDIAN, VARANDT Y. NUPROBE USA, INC. Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing Complete
2019 R21 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Complete
2019 R33 RFA-CA-18-005 LEI, YUGUO UNIVERSITY OF NEBRASKA LINCOLN A Single Conical Tube Device for Precision CAR-T Cells Manufacturing Complete
2019 R21 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Complete
2019 R21 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Complete
2019 R33 RFA-CA-18-003 TAVANA, HOSSEIN UNIVERSITY OF AKRON A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery Complete
2019 R21 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Complete
2019 R33 RFA-CA-18-003 FIOLKA, RETO PAUL UT SOUTHWESTERN MEDICAL CENTER Multiscale microscope for 3D cancer imaging in model organisms and organoids Complete
2019 R21 RFA-CA-18-002 HUANG, XIAOHUA UNIVERSITY OF CALIFORNIA, SAN DIEGO Technology for measuring telomere length of individual chromosomes of single cancer cells Complete
2020 R43 PAR-18-303 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. N6-Methyl-2-O-Methyladenosine Sequencing Complete
2020 R43 PAR-18-303 WANG, SHA VIVID TECHNOLOGIES New specific and rapid assay for in situ apoptosis labeling for cancer studies Complete
2020 R33 RFA-CA-19-020 MATRIX BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories For Targeting Extracellular Matrix Active
2020 R21 RFA-CA-19-019 ALEXANDRAKIS, GEORGIOS UNIVERSITY OF TEXAS ARLINGTON Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy Active
2020 R21 RFA-CA-19-019 LIANG, FU-SEN CASE WESTERN RESERVE UNIVERSITY Spatiotemporal Epitranscriptome Editing Technology Active
2020 R33 RFA-CA-19-020 HIGGINSON, DANIEL SLOAN-KETTERING INST CAN RESEARCH Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways Complete
2020 R33 RFA-CA-19-020 WEI, CHIA-LIN JACKSON LABORATORY Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer Complete
2020 R43 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations Active
2018 R21 RFA-CA-17-010 MAILLOUX, ADAM WILLIAM H. LEE MOFFITT CANCER CTR & RES INST Autohistomagnetic Isolation of Tumor-reactive T-cells Complete
2018 R21 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Complete
2018 R21 RFA-CA-17-010 ABBOTT, KAREN L UNIV OF ARKANSAS FOR MED SCIS Novel platform linking cancer-specific glycosylation with cell signaling outcomes Complete
2018 R21 RFA-CA-17-012 GULLEY, MARGARET L UNIV OF NORTH CAROLINA CHAPEL HILL EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing Complete
2018 R21 RFA-CA-17-012 SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN WAKE FOREST UNIVERSITY HEALTH SCIENCES Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids Complete
2018 R33 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Complete
2018 R33 RFA-CA-17-011 TEWARI, MUNEESH (contact); WALTER, NILS G UNIVERSITY OF MICHIGAN AT ANN ARBOR Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations Complete

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