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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort descending
2021 R21 CA247647 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2020 R21 CA246358 RFA-CA-19-019 SEELIG, GEORG UNIVERSITY OF WASHINGTON High-resolution spatial transcriptomics through light patterning Active
2019 R21 CA229069 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2021 R21 CA250597 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2020 R21 CA247671 RFA-CA-19-019 MARTO, JARROD A DANA-FARBER CANCER INST Tools for DUB Drug Discovery Active
2019 R21 CA235285 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2022 R33 CA267221 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2021 R21 CA251015 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2020 R33 CA240181 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies Active
2019 R21 CA235303 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Active
2018 R21 CA228997 RFA-CA-17-010 ROYZEN, MAKSIM STATE UNIVERSITY OF NEW YORK AT ALBANY Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies Active
2021 R21 CA255894 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2020 R33 CA240191 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2019 R21 CA235305 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Active
2021 R21 CA256081 RFA-CA-20-017 SWAGER, TIMOTHY M MASSACHUSETTS INSTITUTE OF TECHNOLOGY Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation Active
2020 R33 CA246363 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2019 R21 CA235340 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2019 R21 CA236561 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2018 R21 CA223715 RFA-CA-17-010 SHI, TUJIN BATTELLE PACIFIC NORTHWEST LABORATORIES An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells Active
2021 R21 CA256082 RFA-CA-20-017 BAR-PELED, LIRON MASSACHUSETTS GENERAL HOSPITAL Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors Active
2020 R33 CA246455 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2019 R21 CA236594 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2021 R21 CA258019 RFA-CA-20-017 CHEN, KAI UNIVERSITY OF SOUTHERN CALIFORNIA Novel Bisphosphonate PET Probes for Myeloma Bone Disease Active
2020 R33 CA246711 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active
2019 R21 CA236640 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2022 R21 CA257816 CA21-003 COUNTER, CHRISTOPHER M DUKE UNIVERSITY Adapting K-MDS to detect KRAS-mutant ctDNA Active
2021 R33 CA247700 RFA-CA-20-018 JI, HANLEE P STANFORD UNIVERSITY Multimodal iterative sequencing of cancer genomes and single tumor cells Active
2020 R21 CA246359 RFA-CA-19-021 SEIBEL, ERIC J UNIVERSITY OF WASHINGTON Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy Active
2019 R21 CA236685 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2018 R33 CA223947 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Active
2022 R33 CA261696 CA21-004 MERAJVER, SOFIA DIANA UNIVERSITY OF MICHIGAN AT ANN ARBOR Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence Active
2021 R33 CA247744 RFA-CA-20-018 GARTNER, ZEV JORDAN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Universal Sample Multiplexing for Single Cell Analysis Active
2020 R33 CA247669 RFA-CA-19-022 HASHAM, MUNEER GULAMHUSEIN JACKSON LABORATORY Impact of Genetic Diversity on Human Xenograft Tumor Growth Active
2019 R21 CA236690 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active
2018 R33 CA223581 RFA-CA-17-011 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level Active
2022 R33 CA269015 CA21-004 ADEY, ANDREW OREGON HEALTH & SCIENCE UNIVERSITY Accessible high-throughput single-cell genome sequencing Active
2021 R33 CA251006 RFA-CA-20-020 HAUN, JERED BRACKSTON UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic tumor tissue processing platform for single cell diagnostics Active
2020 R43 CA243757 PAR-18-303 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. N6-Methyl-2-O-Methyladenosine Sequencing Active
2019 R21 CA240148 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Active
2022 R33 CA258012 CA21-004 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic Control of Tumor Initiation and Tumor Progression in vivo Active
2021 R33 CA255893 RFA-CA-20-018 SEELIG, GEORG UNIVERSITY OF WASHINGTON Joint receptor and protein expression immunophenotyping through split-pool barcoding Active
2020 R44 CA247353 PAR-18-303 FRIEDA, KIRSTEN SPATIAL GENOMICS, INC. Spatial and single cell analysis of tumor microenvironment by seqFISH+ Active
2019 R21 CA240162 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Active
2018 R33 CA225539 RFA-CA-17-011 JIANG, NING UNIVERSITY OF TEXAS, AUSTIN An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer Active
2022 R21 CA269091 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions Active
2021 R33 CA256102 RFA-CA-20-018 GREENBERG, JOEL DUKE UNIVERSITY Multimodality X-ray transmission and diffraction scanner for molecular analysis of cancer specimens Active
2020 R43 CA250805 PAR-18-303 WANG, SHA VIVID TECHNOLOGIES New specific and rapid assay for in situ apoptosis labeling for cancer studies Active
2019 R21 CA240199 RFA-CA-18-002 O'NEILL, RACHEL UNIVERSITY OF CONNECTICUT STORRS Development and Utilization of Splice-specific Antibodies Active
2022 R33 CA269094 CA21-004 MOELLERING, RAYMOND E UNIVERSITY OF CHICAGO Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues Active
2021 R33 CA257878 RFA-CA-20-018 HANSEN, ANDERS SEJR MASSACHUSETTS INSTITUTE OF TECHNOLOGY Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer Active

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