Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2022 | R33 | CA259451 | RFA-CA-21-004 | NAEGLE, KRISTEN M | UNIVERSITY OF VIRGINIA | A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides | Active |
2021 | R21 | CA255979 | CA20-017 | DIDENKO, VLADIMIR V | BAYLOR COLLEGE OF MEDICINE | In situ assay imaging nuclear RNA exosome activity for cancer studies | Active |
2020 | R33 | CA251037 | RFA-CA-19-020 | WANG, SIYUAN | YALE UNIVERSITY | Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer | Active |
2023 | R33 | CA277820 | RFA-CA-22-002 | WEISSLEDER MD PHD, RALPH | MASSACHUSETTS GENERAL HOSPITAL | Bioorthogonal probe development for highly parallel in vivo imaging | Active |
2021 | R21 | CA261737 | CA20-017 | HAINER, SARAH JANE | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN | Active |
2020 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations | Active |
2023 | R33 | CA278393 | RFA-CA-22-002 | VAN GALEN, PETER | BRIGHAM AND WOMEN'S HOSPITAL | Clonal analysis of cancer by mitochondrial DNA barcoding | Active |
2023 | R33 | CA278551 | RFA-CA-22-002 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | Combining Machine Learning and Nanofluidic Technology for The Multiplexed Diagnosis of Pancreatic Adenocarcinoma | Active |
2021 | R21 | CA251027 | CA20-017 | SCHULMAN, REBECCA | JOHNS HOPKINS UNIVERSITY | Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) | Active |
2023 | R33 | CA278544 | RFA-CA-22-004 | LEVENSON, RICHARD M | UNIVERSITY OF CALIFORNIA AT DAVIS | CoreView and FIBI for rapid-onsite evaluation and molecular profiling of core-needle breast biopsies. | Active |
2023 | R61 | CA281807 | RFA-CA-22-001 | HACOHEN, NIR | BROAD INSTITUTE, INC. | Development of methods for highly multiplexed quantification of cancer proteomes using large-scale nanobody libraries | Active |
2022 | R21 | CA267012 | CA21-003 | SNYDER, JOSHUA CLAIR | DUKE UNIVERSITY | Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color | Active |
2020 | R33 | CA246448 | RFA-CA-19-020 | HALL, ADAM ROGER | WAKE FOREST UNIVERSITY HEALTH SCIENCES | Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores | Active |
2022 | R21 | CA272014 | RFA-CA-21-003 | SALIPANTE, STEPHEN J | UNIVERSITY OF WASHINGTON | Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations | Active |
2022 | R21 | CA250999 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Aliquot-level visual indicators of biospecimen exposure to thawed conditions | Active |
2023 | R33 | CA272331 | RFA-CA-22-002 | MURETTA, JOSEPH M | UNIVERSITY OF MINNESOTA | Engineering Protein Modulators of Notch Activation for T-cell immunotherapy | Active |
2022 | R21 | CA257864 | CA21-003 | BOYLE, ALAN P | UNIVERSITY OF MICHIGAN AT ANN ARBOR | High-throughput inverted reporter assay for characterization of silencers and enhancer blockers | Active |
2021 | R21 | CA236665 | RFA-CA-20-019 | SANTORE, MARIA M | UNIVERSITY OF MASSACHUSETTS AMHERST | Paper-based Breastmilk Collection System for Facile, In-Home Use | Active |
2022 | R21 | CA261642 | RFA-CA-21-003 | NABA, ALEXANDRA | UNIVERSITY OF ILLINOIS AT CHICAGO | Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix | Active |
2022 | R21 | CA258008 | CA21-003 | SCARCELLI, GIULIANO | UNIV OF MARYLAND, COLLEGE PARK | Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential | Active |
2021 | R21 | CA247647 | RFA-CA-20-017 | WILSON, GERALD M | UNIVERSITY OF MARYLAND BALTIMORE | Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases | Active |
2022 | R33 | CA267219 | RFA-CA-21-004 | LANDAU, DAN | WEILL MEDICAL COLL OF CORNELL UNIV | Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes | Active |
2022 | R33 | CA267221 | CA21-004 | NORMAN, THOMAS MAXWELL | SLOAN-KETTERING INST CAN RESEARCH | Systematic characterization of cancer variants using single-cell functional genomics | Active |
2021 | R21 | CA250597 | RFA-CA-20-017 | ZHANG, FANGLIANG | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE | Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) | Active |
2023 | R61 | CA278558 | RFA-CA-22-001 | YAN, HAO | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | High-throughput, purification-free, and ultrasensitive transmembrane nanosensor arrays for digital counting of microRNA biomarkers of intact exosomes | Active |
2022 | R21 | CA267222 | CA21-003 | LEE, HAKHO | MASSACHUSETTS GENERAL HOSPITAL | 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids | Active |
2021 | R21 | CA251015 | RFA-CA-20-017 | STILL, AMANDA NICOLE HAYMOND | GEORGE MASON UNIVERSITY | New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions | Active |
2022 | R21 | CA272326 | RFA-CA-21-003 | KELLY, RYAN T | BRIGHAM YOUNG UNIVERSITY | In-depth and label-free proteome profiling of hundreds of single cells per day | Active |
2022 | R21 | CA257980 | CA21-003 | BELCHER, ANGELA M | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage | Active |
2021 | R21 | CA255894 | RFA-CA-20-017 | XIAO, HAN | RICE UNIVERSITY | Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion | Active |
2023 | R61 | CA281657 | RFA-CA-22-001 | LUKER, GARY D | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Integrated Imaging Tools for Intercellular Chemokine Signalling | Active |
2022 | R33 | CA267226 | CA21-004 | DRAKE, RICHARD R | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids | Active |
2021 | R21 | CA256081 | RFA-CA-20-017 | SWAGER, TIMOTHY M | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation | Active |
2020 | R33 | CA240191 | RFA-CA-19-020 | RECHT, MICHAEL | PALO ALTO RESEARCH CENTER | High-Throughput Screening Platform for Cancer Drug Discovery | Active |
2023 | R61 | CA278402 | RFA-CA-22-001 | BRAVO CORDERO, JOSE JAVIER | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | Intersectional genetics-based biosensors for dormant cancer cells | Active |
2022 | R21 | CA267260 | CA21-003 | ARMITAGE, BRUCE A | CARNEGIE-MELLON UNIVERSITY | Fluorescent gammaPNA Miniprobes for Imaging Telomeric RNA | Active |
2021 | R21 | CA256082 | RFA-CA-20-017 | BAR-PELED, LIRON | MASSACHUSETTS GENERAL HOSPITAL | Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors | Active |
2023 | R33 | CA281875 | RFA-CA-22-004 | BRUDNO, YEVGENY | NORTH CAROLINA STATE UNIVERSITY RALEIGH | MASTER Scaffolds for Rapid, Single-Step Manufacture and Prototyping of CAR-T cells | Active |
2022 | R21 | CA257816 | CA21-003 | COUNTER, CHRISTOPHER M | DUKE UNIVERSITY | Adapting K-MDS to detect KRAS-mutant ctDNA | Active |
2021 | R21 | CA258019 | RFA-CA-20-017 | CHEN, KAI | UNIVERSITY OF SOUTHERN CALIFORNIA | Novel Bisphosphonate PET Probes for Myeloma Bone Disease | Active |
2023 | R33 | CA278392 | RFA-CA-22-002 | KLEIN, ALLON MOSHE | HARVARD MEDICAL SCHOOL | Micro-capsules for versatile multiplexed cytometry | Active |
2022 | R33 | CA261696 | CA21-004 | MERAJVER, SOFIA DIANA | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence | Active |
2021 | R33 | CA247700 | RFA-CA-20-018 | JI, HANLEE P | STANFORD UNIVERSITY | Multimodal iterative sequencing of cancer genomes and single tumor cells | Active |
2020 | R21 | CA246359 | RFA-CA-19-021 | SEIBEL, ERIC J | UNIVERSITY OF WASHINGTON | Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy | Complete |
2000 | R33 | CA083213 | PAR-98-067 | TOLIAS, PETER P | PUBLIC HEALTH RESEARCH INSTITUTE | FUNCTIONAL CLONING OF DNA AND RNA BINDING PROTEINS | Complete |
2002 | R33 | CA091216 | PAR-99-102 | ALLBRITTON, NANCY L | UNIVERSITY OF CALIFORNIA IRVINE | PROFILING RAS ACTIVATED SIGNAL TRANSDUCTION PATHWAYS | Complete |
2006 | R21 | CA120681 | RFA-CA-06-002 | PORTEUS, MATTHEW H | UNIVERSITY OF TEXAS SW MED CTR | DEVELOPMENT OF GENE TARGETING IN C. ELEGANS AND D. RERIO USING ZINC FINGER | Complete |
2008 | R44 | CA134258 | RFA-CA-07-039 | GUO, BAOCHUAN | GLC BIOTECHNOLOGY, INC. | MMPA: A NOVEL MULTIPLEXING METHYLATION ANALYSIS TECHNOLOGY | Complete |
2012 | R21 | CA160060 | RFA-CA-12-002 | WANG, ZHENGHE | CASE WESTERN RESERVE UNIVERSITY | DEVELOPING NOVEL TECHNOLOGY FOR MAPPING DYNAMIC ONCOPROTEIN INTERACTION NETWORKS | Complete |
2015 | R43 | CA193134 | PAR-13-327 | NEVO, EREZ | ROBIN MEDICAL, INC. | COMBINED OPTICAL AND MR MICROSCOPY SYSTEM FOR THIN TISSUE HISTOPATHOLOGY ANALYSIS | Complete |