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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort descending
2022 R21 CA272326 CA21-003 KELLY, RYAN T BRIGHAM YOUNG UNIVERSITY In-depth and label-free proteome profiling of hundreds of single cells per day Active
2020 R21 CA251052 RFA-CA-19-019 SHVETS, GENNADY CORNELL UNIVERSITY Phenotypic Assay For Drug Discovery And Personalized Medicine Based On Real-time Vibrational Spectroscopy Enhanced By Plasmonic Metasurfaces Active
2019 R33 CA236687 RFA-CA-18-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models Active
2022 R21 CA261643 CA21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2020 R21 CA225493 RFA-CA-19-019 TEWARI, MUNEESH UNIVERSITY OF MICHIGAN AT ANN ARBOR Highly Specific, Amplification-free, Single-molecule Counting Of Rare Methylated Dna Cancer Biomarkers Active
2019 R33 CA240201 RFA-CA-18-003 VAN DAM, ROBERT MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research Active
2022 R21 CA272345 CA21-003 KNOWLES, DAVID ARTHUR NEW YORK GENOME CENTER A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer Active
2020 R33 CA251037 RFA-CA-19-020 WANG, SIYUAN YALE UNIVERSITY Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer Active
2019 R21 CA236652 RFA-CA-18-004 SINGAMANENI, SRIKANTH WASHINGTON UNIVERSITY METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION Active
2022 R21 CA272351 CA21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2018 R21 CA229044 RFA-CA-17-010 ABBOTT, KAREN L UNIV OF ARKANSAS FOR MED SCIS Novel platform linking cancer-specific glycosylation with cell signaling outcomes Active
2020 R43 CA236167 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations Active
2019 R21 CA240219 RFA-CA-18-004 ANDRES-MARTIN, LAURA NEW YORK STEM CELL FOUNDATION Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections Active
2022 R33 CA272357 CA21-004 PAN, TAO UNIVERSITY OF CHICAGO Transfer RNA sequencing and application to cancer research and clinics Active
2018 R21 CA223901 RFA-CA-17-010 BRENT, ROGER FRED HUTCHINSON CANCER RESEARCH CENTER Precision controllers of mammalian gene expression Active
2020 R33 CA236681 RFA-CA-19-020 WEI, CHIA-LIN JACKSON LABORATORY Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer Active
2019 R33 CA235326 RFA-CA-18-005 LEI, YUGUO UNIVERSITY OF NEBRASKA LINCOLN A Single Conical Tube Device for Precision CAR-T Cells Manufacturing Active
2022 R33 CA267258 CA21-004 LEE, ABRAHAM P UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy Active
2020 R44 CA250672 PAR-18-303 WINTERS, IAN PAUL D2G ONCOLOGY, INC. Relating Drugs To Genotypes To Transform Precision Cancer Therapeutics With Tuba-seq - A Novel, Highly Scalable And Quantitative Preclinical Experimental Oncology Platform Active
2020 R21 CA229024 RFA-CA-19-019 HUR, SOOJUNG CLAIRE JOHNS HOPKINS UNIVERSITY Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy Active
2022 R21 CA267012 CA21-003 SNYDER, JOSHUA CLAIR DUKE UNIVERSITY Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color Active
2020 R33 CA246448 RFA-CA-19-020 HALL, ADAM ROGER WAKE FOREST UNIVERSITY HEALTH SCIENCES Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores Active
2020 R21 CA236612 RFA-CA-19-019 REVZIN, ALEXANDER MAYO CLINIC ROCHESTER A microfluidic cell culture platform for personalizing pancreatic cancer therapies Active
2019 R21 CA217662 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Active
2018 R21 CA229057 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Active
2022 R21 CA257942 CA21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2020 R33 CA235294 RFA-CA-19-020 WANG, SHAOPENG ARIZONA STATE UNIVERSITY-TEMPE CAMPUS A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics Active
2020 R21 CA236653 RFA-CA-19-019 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics Active
2020 R21 CA240214 RFA-CA-19-019 CICERONE, MARCUS T GEORGIA INSTITUTE OF TECHNOLOGY Label-Free Cell-Resolved Metabolomics for Tumor Microscopy Active
2021 R21 CA236665 RFA-CA-20-019 SANTORE, MARIA M UNIVERSITY OF MASSACHUSETTS AMHERST Paper-based Breastmilk Collection System for Facile, In-Home Use Active
2020 R21 CA246358 RFA-CA-19-019 SEELIG, GEORG UNIVERSITY OF WASHINGTON High-resolution spatial transcriptomics through light patterning Active
2019 R21 CA229069 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2021 R21 CA247647 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2020 R21 CA247671 RFA-CA-19-019 MARTO, JARROD A DANA-FARBER CANCER INST Tools for DUB Drug Discovery Active
2019 R21 CA235285 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2021 R21 CA250597 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2020 R33 CA240181 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies Active
2019 R21 CA235303 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Active
2022 R33 CA267221 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2021 R21 CA251015 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2020 R33 CA240191 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2019 R21 CA235305 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Active
2018 R21 CA228997 RFA-CA-17-010 ROYZEN, MAKSIM STATE UNIVERSITY OF NEW YORK AT ALBANY Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies Active
2021 R21 CA255894 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2020 R33 CA246363 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2019 R21 CA235340 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2021 R21 CA256081 RFA-CA-20-017 SWAGER, TIMOTHY M MASSACHUSETTS INSTITUTE OF TECHNOLOGY Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation Active
2020 R33 CA246455 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2019 R21 CA236561 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2018 R21 CA223715 RFA-CA-17-010 SHI, TUJIN BATTELLE PACIFIC NORTHWEST LABORATORIES An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells Active

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