
Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title |
Status![]() |
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2019 | R21 | CA229069 | RFA-CA-18-002 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants | Active |
2021 | R21 | CA247647 | RFA-CA-20-017 | WILSON, GERALD M | UNIVERSITY OF MARYLAND BALTIMORE | Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases | Active |
2020 | R21 | CA246358 | RFA-CA-19-019 | SEELIG, GEORG | UNIVERSITY OF WASHINGTON | High-resolution spatial transcriptomics through light patterning | Active |
2019 | R21 | CA235285 | RFA-CA-18-002 | KENTSIS, ALEX | SLOAN-KETTERING INST CAN RESEARCH | Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics | Active |
2021 | R21 | CA250597 | RFA-CA-20-017 | ZHANG, FANGLIANG | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE | Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) | Active |
2020 | R21 | CA247671 | RFA-CA-19-019 | MARTO, JARROD A | DANA-FARBER CANCER INST | Tools for DUB Drug Discovery | Active |
2019 | R21 | CA235303 | RFA-CA-18-002 | YAMAMOTO, KEITH ROBERT | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer | Active |
2022 | R33 | CA267221 | CA21-004 | NORMAN, THOMAS MAXWELL | SLOAN-KETTERING INST CAN RESEARCH | Systematic characterization of cancer variants using single-cell functional genomics | Active |
2021 | R21 | CA251015 | RFA-CA-20-017 | STILL, AMANDA NICOLE HAYMOND | GEORGE MASON UNIVERSITY | New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions | Active |
2020 | R33 | CA240181 | RFA-CA-19-020 | COOKS, ROBERT GRAHAM | PURDUE UNIVERSITY | Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies | Active |
2019 | R21 | CA235305 | RFA-CA-18-002 | WU, YUN | STATE UNIVERSITY OF NEW YORK AT BUFFALO | Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection | Active |
2018 | R21 | CA228997 | RFA-CA-17-010 | ROYZEN, MAKSIM | STATE UNIVERSITY OF NEW YORK AT ALBANY | Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies | Active |
2021 | R21 | CA255894 | RFA-CA-20-017 | XIAO, HAN | RICE UNIVERSITY | Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion | Active |
2020 | R33 | CA240191 | RFA-CA-19-020 | RECHT, MICHAEL | PALO ALTO RESEARCH CENTER | High-Throughput Screening Platform for Cancer Drug Discovery | Active |
2019 | R21 | CA235340 | RFA-CA-18-002 | ZHU, YAZHEN | UNIVERSITY OF CALIFORNIA LOS ANGELES | Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs | Active |
2021 | R21 | CA256081 | RFA-CA-20-017 | SWAGER, TIMOTHY M | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation | Active |
2020 | R33 | CA246363 | RFA-CA-19-020 | LEVINSON, NICHOLAS MARK | UNIVERSITY OF MINNESOTA | Time-resolved FRET-based allostery sensors for any protein kinase drug target | Active |
2019 | R21 | CA236561 | RFA-CA-18-002 | WEISSLEDER, RALPH | MASSACHUSETTS GENERAL HOSPITAL | Single Circulating Vesicle Analysis for Early Cancer Detection | Active |
2018 | R21 | CA223715 | RFA-CA-17-010 | SHI, TUJIN | BATTELLE PACIFIC NORTHWEST LABORATORIES | An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells | Active |
2021 | R21 | CA256082 | RFA-CA-20-017 | BAR-PELED, LIRON | MASSACHUSETTS GENERAL HOSPITAL | Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors | Active |
2020 | R33 | CA246455 | RFA-CA-19-020 | CHEN, FEI | BROAD INSTITUTE, INC. | Clinical implementations of spatial transcriptomics in tumors | Active |
2019 | R21 | CA236594 | RFA-CA-18-002 | GARBER, MANUEL | UNIV OF MASSACHUSETTS MED SCH WORCESTER | A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells | Active |
2021 | R21 | CA258019 | RFA-CA-20-017 | CHEN, KAI | UNIVERSITY OF SOUTHERN CALIFORNIA | Novel Bisphosphonate PET Probes for Myeloma Bone Disease | Active |
2020 | R33 | CA246711 | RFA-CA-19-020 | FAN, RONG | YALE UNIVERSITY | High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer | Active |
2019 | R21 | CA236640 | RFA-CA-18-002 | BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories for targeting interstitial fluid pressure | Active |
2022 | R21 | CA257816 | CA21-003 | COUNTER, CHRISTOPHER M | DUKE UNIVERSITY | Adapting K-MDS to detect KRAS-mutant ctDNA | Active |
2021 | R33 | CA247700 | RFA-CA-20-018 | JI, HANLEE P | STANFORD UNIVERSITY | Multimodal iterative sequencing of cancer genomes and single tumor cells | Active |
2020 | R21 | CA246359 | RFA-CA-19-021 | SEIBEL, ERIC J | UNIVERSITY OF WASHINGTON | Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy | Active |
2019 | R21 | CA236685 | RFA-CA-18-002 | MANALIS, SCOTT R | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Building microenvironment-containing organoids from patient samples with single-cell precision | Active |
2018 | R33 | CA223947 | RFA-CA-17-011 | BROWN, BRIAN D | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | Pro-Codes: A novel vector and cell barcoding technology | Active |
2022 | R33 | CA261696 | CA21-004 | MERAJVER, SOFIA DIANA | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence | Active |
2021 | R33 | CA247744 | RFA-CA-20-018 | GARTNER, ZEV JORDAN | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | Universal Sample Multiplexing for Single Cell Analysis | Active |
2020 | R33 | CA247669 | RFA-CA-19-022 | HASHAM, MUNEER GULAMHUSEIN | JACKSON LABORATORY | Impact of Genetic Diversity on Human Xenograft Tumor Growth | Active |
2019 | R21 | CA236690 | RFA-CA-18-002 | KIM, HYUN JUNG | UNIVERSITY OF TEXAS, AUSTIN | A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk | Active |
2018 | R33 | CA223581 | RFA-CA-17-011 | CHENG, JI-XIN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) | Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level | Active |
2022 | R33 | CA269015 | CA21-004 | ADEY, ANDREW | OREGON HEALTH & SCIENCE UNIVERSITY | Accessible high-throughput single-cell genome sequencing | Active |
2021 | R33 | CA251006 | RFA-CA-20-020 | HAUN, JERED BRACKSTON | UNIVERSITY OF CALIFORNIA-IRVINE | Microfluidic tumor tissue processing platform for single cell diagnostics | Active |
2020 | R43 | CA243757 | PAR-18-303 | ERVIN, ERIC | ELECTRONIC BIOSCIENCES, INC. | N6-Methyl-2-O-Methyladenosine Sequencing | Active |
2020 | R44 | CA247353 | PAR-18-303 | FRIEDA, KIRSTEN | SPATIAL GENOMICS, INC. | Spatial and single cell analysis of tumor microenvironment by seqFISH+ | Active |
2019 | R21 | CA240148 | RFA-CA-18-002 | ANGEL, PEGGY M | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins | Active |
2022 | R33 | CA258012 | CA21-004 | KARGINOV, ANDREI V | UNIVERSITY OF ILLINOIS AT CHICAGO | Optogenetic Control of Tumor Initiation and Tumor Progression in vivo | Active |
2021 | R33 | CA255893 | RFA-CA-20-018 | SEELIG, GEORG | UNIVERSITY OF WASHINGTON | Joint receptor and protein expression immunophenotyping through split-pool barcoding | Active |
2020 | R43 | CA250805 | PAR-18-303 | WANG, SHA | VIVID TECHNOLOGIES | New specific and rapid assay for in situ apoptosis labeling for cancer studies | Active |
2019 | R21 | CA240162 | RFA-CA-18-002 | KEUNG, ALBERT | NORTH CAROLINA STATE UNIVERSITY RALEIGH | Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening | Active |
2018 | R33 | CA225539 | RFA-CA-17-011 | JIANG, NING | UNIVERSITY OF TEXAS, AUSTIN | An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer | Active |
2022 | R21 | CA269091 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions | Active |
2021 | R33 | CA256102 | RFA-CA-20-018 | GREENBERG, JOEL | DUKE UNIVERSITY | Multimodality X-ray transmission and diffraction scanner for molecular analysis of cancer specimens | Active |
2020 | R21 | CA240220 | RFA-CA-19-019 | ALEXANDRAKIS, GEORGIOS | UNIVERSITY OF TEXAS ARLINGTON | Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy | Active |
2019 | R21 | CA240199 | RFA-CA-18-002 | O'NEILL, RACHEL | UNIVERSITY OF CONNECTICUT STORRS | Development and Utilization of Splice-specific Antibodies | Active |
2022 | R33 | CA269094 | CA21-004 | MOELLERING, RAYMOND E | UNIVERSITY OF CHICAGO | Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues | Active |