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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort descending Award Type Project # RFA # PI/Project Leader Institution Title Status
2019 R21 CA240219 RFA-CA-18-004 ANDRES-MARTIN, LAURA NEW YORK STEM CELL FOUNDATION Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections Active
2019 R43 CA236103 PAR-18-303 KHODAVERDIAN, VARANDT Y. NUPROBE USA, INC. Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing Complete
2019 R21 CA236561 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2019 R33 CA225549 RFA-CA-18-003 TAVANA, HOSSEIN UNIVERSITY OF AKRON A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery Active
2019 R33 CA235326 RFA-CA-18-005 LEI, YUGUO UNIVERSITY OF NEBRASKA LINCOLN A Single Conical Tube Device for Precision CAR-T Cells Manufacturing Active
2019 R43 CA236167 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations NCE
2019 R21 CA236594 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2019 R33 CA229042 RFA-CA-18-003 SCHNECK, JONATHAN P JOHNS HOPKINS UNIVERSITY A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells Active
2019 R43 CA236177 PAR-18-303 KASOJI, SANDEEP TRIANGLE BIOTECHNOLOGY, INC. SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples Complete
2019 R21 CA236640 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2019 R33 CA229068 RFA-CA-18-003 SCHIAVINATO EBERLIN, LIVIA UNIVERSITY OF TEXAS, AUSTIN Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation Active
2019 R43 CA239967 PAR-18-303 BROWN, MARK T CLAREMONT BIOSOLUTIONS, LLC Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis Complete
2019 R21 CA236685 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2019 R33 CA235254 RFA-CA-18-003 FIOLKA, RETO PAUL UT SOUTHWESTERN MEDICAL CENTER Multiscale microscope for 3D cancer imaging in model organisms and organoids Active
2019 R21 CA217662 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Active
2019 R21 CA236690 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active
2019 R33 CA235302 RFA-CA-18-003 DE VLAMINCK, IWIJN CORNELL UNIVERSITY Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer Active
2019 R21 CA223727 RFA-CA-18-002 HUANG, XIAOHUA UNIVERSITY OF CALIFORNIA, SAN DIEGO Technology for measuring telomere length of individual chromosomes of single cancer cells NCE
2019 R21 CA240148 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Active
2019 R33 CA235319 RFA-CA-18-003 YANG, JENNY J. GEORGIA STATE UNIVERSITY Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment Active
2019 R21 CA229069 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2019 R21 CA240162 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Active
2019 R33 CA235597 RFA-CA-18-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia Active
2019 R21 CA235285 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2020 R21 CA240220 RFA-CA-19-019 ALEXANDRAKIS, GEORGIOS UNIVERSITY OF TEXAS ARLINGTON Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy Active
2020 R21 CA251052 RFA-CA-19-019 SHVETS, GENNADY CORNELL UNIVERSITY Phenotypic Assay For Drug Discovery And Personalized Medicine Based On Real-time Vibrational Spectroscopy Enhanced By Plasmonic Metasurfaces Active
2020 R33 CA240181 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies Active
2020 R33 CA247739 RFA-CA-19-020 MATRIX BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories For Targeting Extracellular Matrix Active
2020 R21 CA225493 RFA-CA-19-019 TEWARI, MUNEESH UNIVERSITY OF MICHIGAN AT ANN ARBOR Highly Specific, Amplification-free, Single-molecule Counting Of Rare Methylated Dna Cancer Biomarkers Active
2020 R33 CA240191 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2020 R33 CA240181 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development Of Desorption Electrospray Ionization Mass Spectrometry For Intraoperative Molecular Diagnosis Of Brain Cancer Using Pathology Biopsies Active
2020 R33 CA251037 RFA-CA-19-020 WANG, SIYUAN YALE UNIVERSITY Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer Active
2020 R33 CA246363 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2020 R21 CA251042 RFA-CA-19-021 GUPTA, GAUTAM UNIVERSITY OF LOUISVILLE Bio Cargos: Capture And Release Gels For Optimized Storage Of Cancer Biospecimens Active
2020 R43 CA236167 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations Active
2020 R33 CA246455 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2020 R44 CA243990 PAR-18-303 GURARD-LEVIN, ZACHARY SAMDI TECH, INC. Development Of The First Label-free And High-throughput, Cell-based Assay That Reports On Specific Enzyme Activities Active
2020 R33 CA236681 RFA-CA-19-020 WEI, CHIA-LIN JACKSON LABORATORY Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer Active
2020 R33 CA246711 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active
2020 R21 CA246457 RFA-CA-19-019 HATTORI, TAKAMITSU NEW YORK UNIVERSITY SCHOOL OF MEDICINE Rational Generation Of High-performance Recombinant Antibodies To Post-translational Modifications Active
2020 R21 CA229024 RFA-CA-19-019 HUR, SOOJUNG CLAIRE JOHNS HOPKINS UNIVERSITY Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy Active
2020 R44 CA250672 PAR-18-303 WINTERS, IAN PAUL D2G ONCOLOGY, INC. Relating Drugs To Genotypes To Transform Precision Cancer Therapeutics With Tuba-seq - A Novel, Highly Scalable And Quantitative Preclinical Experimental Oncology Platform Active
2020 R21 CA246359 RFA-CA-19-021 SEIBEL, ERIC J UNIVERSITY OF WASHINGTON Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy Active
2020 R33 CA236670 RFA-CA-19-020 HIGGINSON, DANIEL SLOAN-KETTERING INST CAN RESEARCH Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways Active
2020 R21 CA236612 RFA-CA-19-019 REVZIN, ALEXANDER MAYO CLINIC ROCHESTER A microfluidic cell culture platform for personalizing pancreatic cancer therapies Active
2020 R33 CA246448 RFA-CA-19-020 HALL, ADAM ROGER WAKE FOREST UNIVERSITY HEALTH SCIENCES Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores Active
2020 R33 CA247669 RFA-CA-19-022 HASHAM, MUNEER GULAMHUSEIN JACKSON LABORATORY Impact of Genetic Diversity on Human Xenograft Tumor Growth Active
2020 R21 CA240185 RFA-CA-19-019 LI, WEI TEXAS TECH UNIVERSITY Fractionation And Profiling Of Heterogeneous Circulating Tumor Cells Using A Hyperuniform- Structured Microchip Active
2020 R21 CA236653 RFA-CA-19-019 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics Active
2020 R33 CA235294 RFA-CA-19-020 WANG, SHAOPENG ARIZONA STATE UNIVERSITY-TEMPE CAMPUS A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics Active

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