Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2019 | R33 | CA225498 | RFA-CA-18-003 | CHEN, SIDI | YALE UNIVERSITY | Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers | Complete |
2019 | R43 | CA236103 | PAR-18-303 | KHODAVERDIAN, VARANDT Y. | NUPROBE USA, INC. | Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing | Complete |
2019 | R21 | CA240219 | RFA-CA-18-004 | ANDRES-MARTIN, LAURA | NEW YORK STEM CELL FOUNDATION | Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections | Complete |
2019 | R21 | CA236561 | RFA-CA-18-002 | WEISSLEDER, RALPH | MASSACHUSETTS GENERAL HOSPITAL | Single Circulating Vesicle Analysis for Early Cancer Detection | Complete |
2019 | R33 | CA225549 | RFA-CA-18-003 | TAVANA, HOSSEIN | UNIVERSITY OF AKRON | A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery | Complete |
2019 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations | Complete |
2019 | R33 | CA235326 | RFA-CA-18-005 | LEI, YUGUO | UNIVERSITY OF NEBRASKA LINCOLN | A Single Conical Tube Device for Precision CAR-T Cells Manufacturing | Complete |
2019 | R21 | CA236594 | RFA-CA-18-002 | GARBER, MANUEL | UNIV OF MASSACHUSETTS MED SCH WORCESTER | A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells | Complete |
2019 | R33 | CA229042 | RFA-CA-18-003 | SCHNECK, JONATHAN P | JOHNS HOPKINS UNIVERSITY | A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells | Complete |
2019 | R43 | CA236177 | PAR-18-303 | KASOJI, SANDEEP | TRIANGLE BIOTECHNOLOGY, INC. | SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples | Complete |
2019 | R21 | CA236640 | RFA-CA-18-002 | BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories for targeting interstitial fluid pressure | Complete |
2019 | R33 | CA229068 | RFA-CA-18-003 | SCHIAVINATO EBERLIN, LIVIA | UNIVERSITY OF TEXAS, AUSTIN | Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation | Complete |
2019 | R43 | CA239967 | PAR-18-303 | BROWN, MARK T | CLAREMONT BIOSOLUTIONS, LLC | Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis | Complete |
2019 | R21 | CA236685 | RFA-CA-18-002 | MANALIS, SCOTT R | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Building microenvironment-containing organoids from patient samples with single-cell precision | Complete |
2019 | R33 | CA235254 | RFA-CA-18-003 | FIOLKA, RETO PAUL | UT SOUTHWESTERN MEDICAL CENTER | Multiscale microscope for 3D cancer imaging in model organisms and organoids | Complete |
2019 | R21 | CA217662 | RFA-CA-18-002 | IM, HYUNGSOON | MASSACHUSETTS GENERAL HOSPITAL | Nano-plasmonic technology for high-throughput single exosome analyses | Complete |
2019 | R21 | CA236690 | RFA-CA-18-002 | KIM, HYUN JUNG | UNIVERSITY OF TEXAS, AUSTIN | A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk | Complete |
2019 | R33 | CA235302 | RFA-CA-18-003 | DE VLAMINCK, IWIJN | CORNELL UNIVERSITY | Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer | Complete |
2019 | R21 | CA223727 | RFA-CA-18-002 | HUANG, XIAOHUA | UNIVERSITY OF CALIFORNIA, SAN DIEGO | Technology for measuring telomere length of individual chromosomes of single cancer cells | Complete |
2019 | R21 | CA240148 | RFA-CA-18-002 | ANGEL, PEGGY M | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins | Complete |
2019 | R33 | CA235319 | RFA-CA-18-003 | YANG, JENNY J. | GEORGIA STATE UNIVERSITY | Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment | Complete |
2019 | R21 | CA229069 | RFA-CA-18-002 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants | Complete |
2020 | R43 | CA250805 | PAR-18-303 | WANG, SHA | VIVID TECHNOLOGIES | New specific and rapid assay for in situ apoptosis labeling for cancer studies | Complete |
2020 | R21 | CA251052 | RFA-CA-19-019 | SHVETS, GENNADY | CORNELL UNIVERSITY | Phenotypic Assay For Drug Discovery And Personalized Medicine Based On Real-time Vibrational Spectroscopy Enhanced By Plasmonic Metasurfaces | Active |
2020 | R21 | CA247671 | RFA-CA-19-019 | MARTO, JARROD A | DANA-FARBER CANCER INST | Tools for DUB Drug Discovery | Complete |
2020 | R21 | CA240220 | RFA-CA-19-019 | ALEXANDRAKIS, GEORGIOS | UNIVERSITY OF TEXAS ARLINGTON | Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy | Active |
2020 | R21 | CA225493 | RFA-CA-19-019 | TEWARI, MUNEESH | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Highly Specific, Amplification-free, Single-molecule Counting Of Rare Methylated Dna Cancer Biomarkers | Active |
2020 | R33 | CA240181 | RFA-CA-19-020 | COOKS, ROBERT GRAHAM | PURDUE UNIVERSITY | Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies | Complete |
2020 | R33 | CA247739 | RFA-CA-19-020 | MATRIX BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories For Targeting Extracellular Matrix | Active |
2020 | R33 | CA251037 | RFA-CA-19-020 | WANG, SIYUAN | YALE UNIVERSITY | Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer | Active |
2020 | R33 | CA240191 | RFA-CA-19-020 | RECHT, MICHAEL | PALO ALTO RESEARCH CENTER | High-Throughput Screening Platform for Cancer Drug Discovery | Active |
2020 | R21 | CA251042 | RFA-CA-19-021 | GUPTA, GAUTAM | UNIVERSITY OF LOUISVILLE | Bio Cargos: Capture And Release Gels For Optimized Storage Of Cancer Biospecimens | Active |
2020 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations | Active |
2020 | R33 | CA246363 | RFA-CA-19-020 | LEVINSON, NICHOLAS MARK | UNIVERSITY OF MINNESOTA | Time-resolved FRET-based allostery sensors for any protein kinase drug target | NCE |
2020 | R44 | CA243990 | PAR-18-303 | GURARD-LEVIN, ZACHARY | SAMDI TECH, INC. | Development Of The First Label-free And High-throughput, Cell-based Assay That Reports On Specific Enzyme Activities | Complete |
2020 | R33 | CA236681 | RFA-CA-19-020 | WEI, CHIA-LIN | JACKSON LABORATORY | Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer | Complete |
2020 | R33 | CA246455 | RFA-CA-19-020 | CHEN, FEI | BROAD INSTITUTE, INC. | Clinical implementations of spatial transcriptomics in tumors | Complete |
2020 | R21 | CA246457 | RFA-CA-19-019 | HATTORI, TAKAMITSU | NEW YORK UNIVERSITY SCHOOL OF MEDICINE | Rational Generation Of High-performance Recombinant Antibodies To Post-translational Modifications | Complete |
2020 | R44 | CA250672 | PAR-18-303 | WINTERS, IAN PAUL | D2G ONCOLOGY, INC. | Relating Drugs To Genotypes To Transform Precision Cancer Therapeutics With Tuba-seq - A Novel, Highly Scalable And Quantitative Preclinical Experimental Oncology Platform | Complete |
2020 | R33 | CA246711 | RFA-CA-19-020 | FAN, RONG | YALE UNIVERSITY | High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer | Complete |
2020 | R33 | CA236670 | RFA-CA-19-020 | HIGGINSON, DANIEL | SLOAN-KETTERING INST CAN RESEARCH | Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways | Complete |
2020 | R33 | CA246448 | RFA-CA-19-020 | HALL, ADAM ROGER | WAKE FOREST UNIVERSITY HEALTH SCIENCES | Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores | Active |
2020 | R21 | CA229024 | RFA-CA-19-019 | HUR, SOOJUNG CLAIRE | JOHNS HOPKINS UNIVERSITY | Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy | Complete |
2020 | R21 | CA246359 | RFA-CA-19-021 | SEIBEL, ERIC J | UNIVERSITY OF WASHINGTON | Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy | Complete |
2020 | R21 | CA240185 | RFA-CA-19-019 | LI, WEI | TEXAS TECH UNIVERSITY | Fractionation And Profiling Of Heterogeneous Circulating Tumor Cells Using A Hyperuniform- Structured Microchip | Active |
2020 | R33 | CA235294 | RFA-CA-19-020 | WANG, SHAOPENG | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics | Complete |
2020 | R21 | CA236612 | RFA-CA-19-019 | REVZIN, ALEXANDER | MAYO CLINIC ROCHESTER | A microfluidic cell culture platform for personalizing pancreatic cancer therapies | NCE |
2020 | R33 | CA247669 | RFA-CA-19-022 | HASHAM, MUNEER GULAMHUSEIN | JACKSON LABORATORY | Impact of Genetic Diversity on Human Xenograft Tumor Growth | Complete |
2020 | R21 | CA247638 | RFA-CA-19-019 | LIANG, FU-SEN | CASE WESTERN RESERVE UNIVERSITY | Spatiotemporal Epitranscriptome Editing Technology | Active |
2020 | R21 | CA236653 | RFA-CA-19-019 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics | NCE |