Grants Awarded

Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort descending Award Type Project # RFA # PI/Project Leader Institution Title Status
2020 R33 RFA-CA-19-020 WEI, CHIA-LIN JACKSON LABORATORY Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer Active
2020 R33 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active
2020 R21 RFA-CA-19-019 HATTORI, TAKAMITSU NEW YORK UNIVERSITY SCHOOL OF MEDICINE Rational Generation Of High-performance Recombinant Antibodies To Post-translational Modifications Active
2020 R44 PAR-18-303 WINTERS, IAN PAUL D2G ONCOLOGY, INC. Relating Drugs To Genotypes To Transform Precision Cancer Therapeutics With Tuba-seq - A Novel, Highly Scalable And Quantitative Preclinical Experimental Oncology Platform Active
2020 R21 RFA-CA-19-019 HUR, SOOJUNG CLAIRE JOHNS HOPKINS UNIVERSITY Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy Active
2020 R21 RFA-CA-19-021 SEIBEL, ERIC J UNIVERSITY OF WASHINGTON Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy Active
2020 R33 RFA-CA-19-020 HIGGINSON, DANIEL SLOAN-KETTERING INST CAN RESEARCH Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways Active
2020 R33 RFA-CA-19-020 HALL, ADAM ROGER WAKE FOREST UNIVERSITY HEALTH SCIENCES Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores Active
2020 R21 RFA-CA-19-019 REVZIN, ALEXANDER MAYO CLINIC ROCHESTER A microfluidic cell culture platform for personalizing pancreatic cancer therapies Active
2021 R33 RFA-CA-20-018 GARTNER, ZEV JORDAN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Universal Sample Multiplexing for Single Cell Analysis Active
2021 R21 CA20-017 BHARGAVA, ROHIT UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Spectroscopy Assisted Laser Microdissection Complete
2021 R33 RFA-CA-20-020 HAUN, JERED BRACKSTON UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic tumor tissue processing platform for single cell diagnostics Active
2021 R33 CA20-018 ZENG, YONG UNIVERSITY OF FLORIDA Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles Complete
2021 R21 RFA-CA-20-019 SANTORE, MARIA M UNIVERSITY OF MASSACHUSETTS AMHERST Paper-based Breastmilk Collection System for Facile, In-Home Use Active
2021 R33 RFA-CA-20-018 SEELIG, GEORG UNIVERSITY OF WASHINGTON Joint receptor and protein expression immunophenotyping through split-pool barcoding Active
2021 R33 CA20-018 JIANG, NING JENNY UNIVERSITY OF PENNSYLVANIA A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells Complete
2021 R21 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2021 R33 RFA-CA-20-018 GREENBERG, JOEL DUKE UNIVERSITY Multimodality X-ray transmission and diffraction scanner for molecular analysis of cancer specimens Active
2021 R33 CA20-018 WEI, WEI INSTITUTE FOR SYSTEMS BIOLOGY Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy Complete
2021 R21 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2021 R33 RFA-CA-20-018 HANSEN, ANDERS SEJR MASSACHUSETTS INSTITUTE OF TECHNOLOGY Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer Active
2021 R33 CA20-018 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy Complete
2021 R21 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2021 R33 RFA-CA-20-018 LIU, XUEFENG OHIO STATE UNIVERSITY Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics Active
2021 R21 CA20-017 FARIS, GREGORY W NUMENTUS TECHNOLOGIES INC. Decoding Individual Exosomes in Cancer Complete
2021 R21 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2021 R44 PAR-18-303 HUNG, PAUL JU-SUNG COMBINATI, INC. Digital Melt Curve Analysis Platform for Longitudinal Cancer Patient Monitoring Active
2021 R21 CA20-017 DIDENKO, VLADIMIR V BAYLOR COLLEGE OF MEDICINE In situ assay imaging nuclear RNA exosome activity for cancer studies Complete
2021 R21 RFA-CA-20-017 SWAGER, TIMOTHY M MASSACHUSETTS INSTITUTE OF TECHNOLOGY Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation Active
2021 R21 CA20-017 HOSHIKA, SHUICHI FOUNDATION FOR APPLIED MOLECULAR EVOLUTN High Quality Proteins with Multiple Post Translational Modifications Complete
2021 R21 CA20-017 HAINER, SARAH JANE UNIVERSITY OF PITTSBURGH AT PITTSBURGH Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN Complete
2021 R21 RFA-CA-20-017 BAR-PELED, LIRON MASSACHUSETTS GENERAL HOSPITAL Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors Active
2021 R21 CA20-017 DI CARLO, DINO UNIVERSITY OF CALIFORNIA LOS ANGELES Lab on a particle technology for functional screening of therapeutic cells Complete
2021 R21 CA20-017 DEININGER, MICHAEL W VERSITI WISCONSIN, INC. A Bioluminescent Assay for Direct Measurement of Sirtuin Activity in Cancer Cells Complete
2021 R21 RFA-CA-20-017 CHEN, KAI UNIVERSITY OF SOUTHERN CALIFORNIA Novel Bisphosphonate PET Probes for Myeloma Bone Disease Active
2021 R21 CA20-019 NAUTIYAL, SHIVANI PRIME GENOMICS, INC. Device for Preservation of Cell Free RNA in Saliva Complete
2021 R21 CA20-017 SCHULMAN, REBECCA JOHNS HOPKINS UNIVERSITY Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) Complete
2021 R33 RFA-CA-20-018 JI, HANLEE P STANFORD UNIVERSITY Multimodal iterative sequencing of cancer genomes and single tumor cells Active
2021 R21 CA20-019 AKSAN, ALPTEKIN UNIVERSITY OF MINNESOTA Novel cryopreservation method for stabilization of manufactured therapeutic cells Complete
2022 R33 CA21-004 MERAJVER, SOFIA DIANA UNIVERSITY OF MICHIGAN AT ANN ARBOR Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence Active
2022 R21 CA21-005 SHIBATA, DARRYL K UNIVERSITY OF SOUTHERN CALIFORNIA Photolithographic Tumor DNA Isolation Active
2022 R21 CA21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2022 R33 CA21-004 ADEY, ANDREW OREGON HEALTH & SCIENCE UNIVERSITY Accessible high-throughput single-cell genome sequencing Active
2022 R33 CA21-004 LANDAU, DAN WEILL MEDICAL COLL OF CORNELL UNIV Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes Active
2022 R21 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Aliquot-level visual indicators of biospecimen exposure to thawed conditions Complete
2022 R33 CA21-004 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic Control of Tumor Initiation and Tumor Progression in vivo Active
2022 R33 CA21-004 WANG, TZA-HUEI JEFF JOHNS HOPKINS UNIVERSITY A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies Active
2022 R21 CA21-003 BOYLE, ALAN P UNIVERSITY OF MICHIGAN AT ANN ARBOR High-throughput inverted reporter assay for characterization of silencers and enhancer blockers Complete
2022 R21 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions Active
2022 R33 CA21-004 NAEGLE, KRISTEN M UNIVERSITY OF VIRGINIA A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides Active