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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort ascending Award Type Project # RFA # PI/Project Leader Institution Title Status
2018 R21 CA223715 RFA-CA-17-010 SHI, TUJIN BATTELLE PACIFIC NORTHWEST LABORATORIES An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells Active
2018 R33 CA228979 RFA-CA-17-011 SCHRUM, ADAM G UNIVERSITY OF MISSOURI-COLUMBIA Multiplex matrix ELISA for T cell protein-interaction networks in cancer Active
2018 R21 CA223901 RFA-CA-17-010 BRENT, ROGER FRED HUTCHINSON CANCER RESEARCH CENTER Precision controllers of mammalian gene expression Active
2018 R21 CA223887 RFA-CA-17-010 SMITH, LLOYD M UNIVERSITY OF WISCONSIN-MADISON Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues NCE
2018 R33 CA229023 RFA-CA-17-011 TEWARI, MUNEESH (contact); WALTER, NILS G UNIVERSITY OF MICHIGAN AT ANN ARBOR Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations Active
2018 R21 CA217735 RFA-CA-17-010 ENGLER, ADAM JEFFREY UNIVERSITY OF CALIFORNIA, SAN DIEGO Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells Complete
2018 R21 CA214239 RFA-CA-17-010 VAN DEVENTER, JAMES ALLEN TUFTS UNIVERSITY MEDFORD Discovering hybrid inhibitors for tumor microenvironment disruption NCE
2018 R21 CA229037 RFA-CA-17-012 GULLEY, MARGARET L UNIV OF NORTH CAROLINA CHAPEL HILL EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing Active
2018 R21 CA223836 RFA-CA-17-010 FIELDS, RYAN C WASHINGTON UNIVERSITY Advancing Cancer Biology, Diagnostics and Therapeutics Outside of the Patient: Creation of a Novel, Autologous, Ex Vivo, Vascularized Model of the Tumor Microenvironment NCE
2018 R33 CA223947 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Active
2018 R21 CA225507 RFA-CA-17-012 PAULOVICH, AMANDA G FRED HUTCHINSON CANCER RESEARCH CENTER Validation of a disposable biospecimen collection system with integral refrigeration for preserving the phosphoproteome NCE
2018 R21 CA229057 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Active
2018 R33 CA223581 RFA-CA-17-011 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level Active
2018 R21 CA229027 RFA-CA-17-012 SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN WAKE FOREST UNIVERSITY HEALTH SCIENCES Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids Complete
2018 R21 CA223915 RFA-CA-17-010 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic tools for the dissection of oncogenic signaling mediated by kinases NCE
2018 R33 CA223904 RFA-CA-17-011 CIMA, MICHAEL J MASSACHUSETTS INSTITUTE OF TECHNOLOGY Advanced development and validation of microdevices for high-throughput in situ drug sensitivity testing in tumors NCE
2018 R33 CA217702 RFA-CA-17-013 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Validation and Advanced Development of Albumin Oxidizability as a Marker of Plasma/Serum Integrity Active
2017 R21 CA212958 RFA-CA-16-001 KESHARI, KAYVAN R. SLOAN-KETTERING INST CAN RESEARCH uCoil NMR platform for robust and high-throughput analysis of in vitro metabolic flux on living cells Complete
2017 R33 CA204704 RFA-CA-16-002 WANG, YINGXIAO UNIVERSITY OF CALIFORNIA, SAN DIEGO Multiplex FRET Imaging of Kinase-Epigenome Interregulations in Live Cancer Cells Complete
2017 R33 CA217700 RFA-CA-16-002 WALTER, MATTHEW J WASHINGTON UNIVERSITY TARGETED SINGLE-MOLECULE SEQUENCING ASSAY INCORPORATING MOLECULAR BARCODES NCE
2017 R21 CA204708 RFA-CA-16-001 MALMSTADT, NOAH UNIVERSITY OF SOUTHERN CALIFORNIA A Target-Directed Reagent Pipeline via Microfluidic mRNA Display Complete
2017 R21 CA212967 RFA-CA-16-001 WINDLE, BRAD E. VIRGINIA COMMONWEALTH UNIVERSITY The GOF Mutant p53 Beacon System Complete
2017 R33 CA206907 RFA-CA-16-004 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA Rapid unbiased isolation and in situ RNA analysis of circulating tumor cells using a magnetic micropore-based diagnostic chip NCE
2017 R33 CA217780 RFA-CA-16-002 PARKER, LAURIE L. UNIVERSITY OF MINNESOTA Fluorescence lifetime-based single fluorophore biosensors of post-translational modification enzyme activity NCE
2017 R21 CA212495 RFA-CA-16-001 EASWARAN, HARIHARAN JOHNS HOPKINS UNIVERSITY High-efficiency microfluidic-assisted single-cell DNA methylome sequencing NCE
2017 R21 CA213234 RFA-CA-16-003 WELJIE, AALIM M UNIVERSITY OF PENNSYLVANIA Determining and enhancing metabolite fitness for metabolomics measurements Complete
2017 R33 CA206939 RFA-CA-16-004 PATTENDEN, SAMANTHA GAIL UNIV OF NORTH CAROLINA CHAPEL HILL The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues NCE
2017 R43 CA214386 PAR-13-327 PEYTAVI, REGIS BLUENOVO BIOSYSTEMS, INC. Detection of Methylation and Translocation Events by Novel Sequencing Technology Complete
2017 R21 CA212500 RFA-CA-16-001 MOHS, AARON M. UNIVERSITY OF NEBRASKA MEDICAL CENTER Tunable Fluorescent Organic Nanoparticles for Cancer Imaging Applications NCE
2017 R21 CA213247 RFA-CA-16-001 KRON, STEPHEN J. UNIVERSITY OF CHICAGO Tag-ChIP-MS for analysis of chromatin-level regulation of DNA repair Complete
2017 R33 CA212697 RFA-CA-16-002 KLEIN, ALLON MOSHE HARVARD MEDICAL SCHOOL Droplet microfluidic technology for single cell cancer genomics Complete
2017 R44 CA188154 PAR-13-327 PREMSRIRUT, PREM KHOVABUTR MIRIMUS, INC. Next generation CRISPR/Cas9-RNAi mouse models for accelerated drug discovery research Complete
2017 R21 CA212718 RFA-CA-16-001 VAN DAM, ROBERT MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES High-throughput radiochemistry platform for accelerated discovery and development of novel PET imaging agents for cancer Complete
2017 R21 CA214233 RFA-CA-16-001 SOELLNER, MATTHEW B UNIVERSITY OF MICHIGAN AT ANN ARBOR Exquisitely selective turn-on probes of kinase activation and localization NCE
2017 R33 CA212806 RFA-CA-16-004 ZILBERBERG, JENNY HACKENSACK UNIVERSITY MEDICAL CENTER Ex vivo culture platform validation for preservation of patient derived multiple myeloma cells NCE
2017 R21 CA212726 RFA-CA-16-001 NAEGLE, KRISTEN M WASHINGTON UNIVERSITY A MOLECULAR TOOLKIT FOR THE PRODUCTION OF TYROSINE PHOSPHORYLATED PROTEINS NCE
2017 R21 CA214299 RFA-CA-16-001 SLATER, JOHN HUNDLEY UNIVERSITY OF DELAWARE A Vascularized, In Vitro, Organotropic Metastasis Model to Generate Dormant Micrometastases NCE
2017 R33 CA212968 RFA-CA-16-002 SINGH, ANKUR CORNELL UNIVERSITY LETSSGo: Lymphoma-on-chip Engineered Technology for Single-Organoid Sequencing and Genomics Complete
2017 R21 CA212731 RFA-CA-16-001 DAVIS, RONALD WAYNE STANFORD UNIVERSITY Nanoneedle microrobots for single cancer cell manipulation and genome editing Complete
2017 R21 CA217695 RFA-CA-16-001 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA A novel time-resolved fluorescence-based high-throughput screening technology for discovering allosteric kinase inhibitors Complete
2017 R33 CA212973 RFA-CA-16-002 YATES, JOHN R SCRIPPS RESEARCH INSTITUTE Measurement of Aberrant Protein Folds in Malignant Cells with Proteomics and Mass Spectrometry Complete
2017 R21 CA212827 RFA-CA-16-001 WONG, WESLEY PHILIP BOSTON CHILDREN'S HOSPITAL Single-molecule mechanical detection of protein and microRNA cancer biomarkers Complete
2017 R21 CA217751 RFA-CA-16-003 NECHAEV, SERGEI UNIVERSITY OF NORTH DAKOTA Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments. NCE
2017 R33 CA214176 RFA-CA-16-002 LU, CHANG VIRGINIA POLYTECHNIC INST AND ST UNIV Next-generation MOWChIP-seq for high-throughput epigenomic profiling using clinically relevant samples Complete
2017 R21 CA212907 RFA-CA-16-001 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Engineered regulation of tyrosine phosphatase activity in living cells NCE
2017 R21 CA217754 RFA-CA-16-001 DICKINSON, BRYAN UNIVERSITY OF CHICAGO rePPI-i: A system for the rapid continuous evolution of protein-protein interaction inhibitors NCE
2017 R33 CA214333 RFA-CA-16-002 ZENG, YONG UNIVERSITY OF KANSAS LAWRENCE Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer Complete
2017 R21 CA212928 RFA-CA-16-001 BROCK, AMY UNIVERSITY OF TEXAS, AUSTIN High resolution cell lineage tracking and isolation NCE
2017 R33 CA202881 RFA-CA-16-002 LEVENSON, RICHARD M. UNIVERSITY OF CALIFORNIA AT DAVIS Cancer histology and QC via MUSE: Sample-sparing UV surface-excitation microscopy Complete
2017 R33 CA217652 RFA-CA-16-002 MAKRIGIORGOS, G. MIKE DANA-FARBER CANCER INST Maximum efficiency sequencing using nuclease-based mutation enrichment and digital barcodes NCE

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