Grants Awarded

Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort ascending
2022 R33 CA21-004 LEE, ABRAHAM P UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy Active
2020 R44 PAR-18-303 WINTERS, IAN PAUL D2G ONCOLOGY, INC. Relating Drugs To Genotypes To Transform Precision Cancer Therapeutics With Tuba-seq - A Novel, Highly Scalable And Quantitative Preclinical Experimental Oncology Platform Active
2020 R21 RFA-CA-19-019 HUR, SOOJUNG CLAIRE JOHNS HOPKINS UNIVERSITY Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy Active
2023 R61 RFA-CA-22-001 GAO, XIAOJING J STANFORD UNIVERSITY Program the Immune System against RAS-driven Cancer Active
2022 R21 RFA-CA-21-003 KNOWLES, DAVID ARTHUR NEW YORK GENOME CENTER A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer Active
2022 R21 CA21-003 SNYDER, JOSHUA CLAIR DUKE UNIVERSITY Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color Active
2020 R33 RFA-CA-19-020 HALL, ADAM ROGER WAKE FOREST UNIVERSITY HEALTH SCIENCES Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores Active
2020 R21 RFA-CA-19-019 REVZIN, ALEXANDER MAYO CLINIC ROCHESTER A microfluidic cell culture platform for personalizing pancreatic cancer therapies Active
2023 R33 RFA-CA-22-002 CUNNINGHAM, BRIAN T UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopy Active
2019 R21 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Active
2023 R61 RFA-CA-22-001 SHAH, NEEL H COLUMBIA UNIV NEW YORK MORNINGSIDE A Generalizable Photo-Crosslinking Strategy to Identify Tyrosine Phosphatase Substrates Active
2018 R21 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Active
2022 R21 CA21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2020 R33 RFA-CA-19-020 WANG, SHAOPENG ARIZONA STATE UNIVERSITY-TEMPE CAMPUS A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics Active
2020 R21 RFA-CA-19-019 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics Active
2023 R33 RFA-CA-22-002 JI, HANLEE P STANFORD UNIVERSITY Single cell modeling of cancer mutations Active
2023 R33 RFA-CA-22-002 MEYER, KATHRYN D DUKE UNIVERSITY A High-Throughput Screening Platform to Discover RNA Methylation Inhibitors Active
2021 R21 RFA-CA-20-019 SANTORE, MARIA M UNIVERSITY OF MASSACHUSETTS AMHERST Paper-based Breastmilk Collection System for Facile, In-Home Use Active
2020 R21 RFA-CA-19-019 CICERONE, MARCUS T GEORGIA INSTITUTE OF TECHNOLOGY Label-Free Cell-Resolved Metabolomics for Tumor Microscopy Active
2023 R61 RFA-CA-22-001 DHAKAL, SOMA VIRGINIA COMMONWEALTH UNIVERSITY Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers Active
2019 R21 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2022 R33 RFA-CA-21-004 WANG, TZA-HUEI JEFF JOHNS HOPKINS UNIVERSITY A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies Active
2021 R21 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2020 R21 RFA-CA-19-019 SEELIG, GEORG UNIVERSITY OF WASHINGTON High-resolution spatial transcriptomics through light patterning Active
2022 R33 RFA-CA-21-004 PAN, TAO UNIVERSITY OF CHICAGO Transfer RNA sequencing and application to cancer research and clinics Active
2019 R21 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2022 R21 RFA-CA-21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2021 R21 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2020 R21 RFA-CA-19-019 MARTO, JARROD A DANA-FARBER CANCER INST Tools for DUB Drug Discovery Active
2023 R61 RFA-CA-22-001 LU, YUE UNIVERSITY OF UTAH Vesicle Epitope Transcript sequencing (VET-seq): Droplet-based Multiomic Profiling Platform for Single Vesicle Analysis Active
2019 R21 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Active
2023 R61 RFA-CA-22-001 PRATX, GUILLEM STANFORD UNIVERSITY A Novel Assay to Individualize Resensitization of Iodine-Refractory Thyroid Cancer Active
2022 R33 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2021 R21 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2020 R33 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies Active
2019 R21 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Active
2022 R21 RFA-CA-21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2018 R21 RFA-CA-17-010 ROYZEN, MAKSIM STATE UNIVERSITY OF NEW YORK AT ALBANY Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies Active
2021 R21 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2020 R33 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2020 R33 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2019 R21 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2023 R61 RFA-CA-22-001 CAMPAGNOLA, PAUL J UNIVERSITY OF WISCONSIN-MADISON A novel multimodal ECM analysis platform for tumor characterization combining morphological and spectrochemical tissue imaging approaches. Active
2021 R21 RFA-CA-20-017 SWAGER, TIMOTHY M MASSACHUSETTS INSTITUTE OF TECHNOLOGY Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation Active
2020 R33 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2019 R21 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2023 R33 RFA-CA-22-004 DUNCAVAGE, ERIC J WASHINGTON UNIVERSITY A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer Active
2018 R21 RFA-CA-17-010 SHI, TUJIN BATTELLE PACIFIC NORTHWEST LABORATORIES An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells Active
2021 R21 RFA-CA-20-017 BAR-PELED, LIRON MASSACHUSETTS GENERAL HOSPITAL Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors Active
2020 R33 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active