Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
| Year | Award Type |
Project # |
RFA # | PI/Project Leader | Institution | Title | Status |
|---|---|---|---|---|---|---|---|
| 2017 | R33 | CA212697 | RFA-CA-16-002 | KLEIN, ALLON MOSHE | HARVARD MEDICAL SCHOOL | Droplet microfluidic technology for single cell cancer genomics | Complete |
| 2017 | R21 | CA212718 | RFA-CA-16-001 | VAN DAM, ROBERT MICHAEL | UNIVERSITY OF CALIFORNIA LOS ANGELES | High-throughput radiochemistry platform for accelerated discovery and development of novel PET imaging agents for cancer | Complete |
| 2017 | R21 | CA212731 | RFA-CA-16-001 | DAVIS, RONALD WAYNE | STANFORD UNIVERSITY | Nanoneedle microrobots for single cancer cell manipulation and genome editing | Complete |
| 2017 | R21 | CA212827 | RFA-CA-16-001 | WONG, WESLEY PHILIP | BOSTON CHILDREN'S HOSPITAL | Single-molecule mechanical detection of protein and microRNA cancer biomarkers | Complete |
| 2017 | R33 | CA204574 | RFA-CA-16-002 | KELLEY, SHANA O | UNIVERSITY OF TORONTO | Development and validation of nanoparticle-mediated microfluidic profiling approach for rare cell analysis | Complete |
| 2017 | R21 | CA204560 | RFA-CA-16-001 | WALTER, NILS G | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Single-molecule counting of cancer biomarker miRNAs in human biofluids | Complete |
| 2017 | R21 | CA212958 | RFA-CA-16-001 | KESHARI, KAYVAN R. | SLOAN-KETTERING INST CAN RESEARCH | uCoil NMR platform for robust and high-throughput analysis of in vitro metabolic flux on living cells | Complete |
| 2017 | R21 | CA212967 | RFA-CA-16-001 | WINDLE, BRAD E. | VIRGINIA COMMONWEALTH UNIVERSITY | The GOF Mutant p53 Beacon System | Complete |
| 2017 | R33 | CA212968 | RFA-CA-16-002 | SINGH, ANKUR | CORNELL UNIVERSITY | LETSSGo: Lymphoma-on-chip Engineered Technology for Single-Organoid Sequencing and Genomics | Complete |
| 2017 | R33 | CA212973 | RFA-CA-16-002 | YATES, JOHN R | SCRIPPS RESEARCH INSTITUTE | Measurement of Aberrant Protein Folds in Malignant Cells with Proteomics and Mass Spectrometry | Complete |
| 2017 | R33 | CA202881 | RFA-CA-16-002 | LEVENSON, RICHARD M. | UNIVERSITY OF CALIFORNIA AT DAVIS | Cancer histology and QC via MUSE: Sample-sparing UV surface-excitation microscopy | Complete |
| 2017 | R21 | CA213234 | RFA-CA-16-003 | WELJIE, AALIM M | UNIVERSITY OF PENNSYLVANIA | Determining and enhancing metabolite fitness for metabolomics measurements | Complete |
| 2017 | R21 | CA213247 | RFA-CA-16-001 | KRON, STEPHEN J. | UNIVERSITY OF CHICAGO | Tag-ChIP-MS for analysis of chromatin-level regulation of DNA repair | Complete |
| 2017 | R33 | CA206907 | RFA-CA-16-004 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | Rapid unbiased isolation and in situ RNA analysis of circulating tumor cells using a magnetic micropore-based diagnostic chip | NCE |
| 2017 | R33 | CA214176 | RFA-CA-16-002 | LU, CHANG | VIRGINIA POLYTECHNIC INST AND ST UNIV | Next-generation MOWChIP-seq for high-throughput epigenomic profiling using clinically relevant samples | Complete |
| 2017 | R43 | CA214386 | PAR-13-327 | PEYTAVI, REGIS | BLUENOVO BIOSYSTEMS, INC. | Detection of Methylation and Translocation Events by Novel Sequencing Technology | Complete |
| 2017 | R21 | CA214233 | RFA-CA-16-001 | SOELLNER, MATTHEW B | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Exquisitely selective turn-on probes of kinase activation and localization | NCE |
| 2017 | R21 | CA214299 | RFA-CA-16-001 | SLATER, JOHN HUNDLEY | UNIVERSITY OF DELAWARE | A Vascularized, In Vitro, Organotropic Metastasis Model to Generate Dormant Micrometastases | NCE |
| 2017 | R33 | CA206939 | RFA-CA-16-004 | PATTENDEN, SAMANTHA GAIL | UNIV OF NORTH CAROLINA CHAPEL HILL | The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues | NCE |
| 2017 | R33 | CA214333 | RFA-CA-16-002 | ZENG, YONG | UNIVERSITY OF KANSAS LAWRENCE | Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer | Complete |
| 2017 | R33 | CA204704 | RFA-CA-16-002 | WANG, YINGXIAO | UNIVERSITY OF CALIFORNIA, SAN DIEGO | Multiplex FRET Imaging of Kinase-Epigenome Interregulations in Live Cancer Cells | Complete |
| 2017 | R21 | CA204708 | RFA-CA-16-001 | MALMSTADT, NOAH | UNIVERSITY OF SOUTHERN CALIFORNIA | A Target-Directed Reagent Pipeline via Microfluidic mRNA Display | Complete |
| 2017 | R44 | CA188154 | PAR-13-327 | PREMSRIRUT, PREM KHOVABUTR | MIRIMUS, INC. | Next generation CRISPR/Cas9-RNAi mouse models for accelerated drug discovery research | Complete |
| 2017 | R33 | CA217652 | RFA-CA-16-002 | MAKRIGIORGOS, G. MIKE | DANA-FARBER CANCER INST | Maximum efficiency sequencing using nuclease-based mutation enrichment and digital barcodes | NCE |
| 2017 | R21 | CA212495 | RFA-CA-16-001 | EASWARAN, HARIHARAN | JOHNS HOPKINS UNIVERSITY | High-efficiency microfluidic-assisted single-cell DNA methylome sequencing | NCE |
| 2017 | R21 | CA217695 | RFA-CA-16-001 | LEVINSON, NICHOLAS MARK | UNIVERSITY OF MINNESOTA | A novel time-resolved fluorescence-based high-throughput screening technology for discovering allosteric kinase inhibitors | Complete |
| 2017 | R33 | CA217699 | RFA-CA-16-002 | IBRAHIM, YEHIA | BATTELLE PACIFIC NORTHWEST LABORATORIES | High Resolution High Throughput Proteomics Platform for Cancer Research | NCE |
| 2017 | R33 | CA217700 | RFA-CA-16-002 | WALTER, MATTHEW J | WASHINGTON UNIVERSITY | TARGETED SINGLE-MOLECULE SEQUENCING ASSAY INCORPORATING MOLECULAR BARCODES | NCE |
| 2017 | R33 | CA212806 | RFA-CA-16-004 | ZILBERBERG, JENNY | HACKENSACK UNIVERSITY MEDICAL CENTER | Ex vivo culture platform validation for preservation of patient derived multiple myeloma cells | NCE |
| 2017 | R21 | CA212928 | RFA-CA-16-001 | BROCK, AMY | UNIVERSITY OF TEXAS, AUSTIN | High resolution cell lineage tracking and isolation | NCE |
| 2017 | R21 | CA212907 | RFA-CA-16-001 | KARGINOV, ANDREI V | UNIVERSITY OF ILLINOIS AT CHICAGO | Engineered regulation of tyrosine phosphatase activity in living cells | NCE |
| 2017 | R21 | CA217751 | RFA-CA-16-003 | NECHAEV, SERGEI | UNIVERSITY OF NORTH DAKOTA | Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments. | NCE |
| 2017 | R21 | CA217754 | RFA-CA-16-001 | DICKINSON, BRYAN | UNIVERSITY OF CHICAGO | rePPI-i: A system for the rapid continuous evolution of protein-protein interaction inhibitors | NCE |
| 2017 | R21 | CA212932 | RFA-CA-16-001 | WONG, IAN Y | BROWN UNIVERSITY | High Content Screening of Multicellular Invasion with 3D Traction Force Microscopy | Complete |
| 2017 | R33 | CA217780 | RFA-CA-16-002 | PARKER, LAURIE L. | UNIVERSITY OF MINNESOTA | Fluorescence lifetime-based single fluorophore biosensors of post-translational modification enzyme activity | NCE |
| 2017 | R21 | CA212726 | RFA-CA-16-001 | NAEGLE, KRISTEN M | WASHINGTON UNIVERSITY | A MOLECULAR TOOLKIT FOR THE PRODUCTION OF TYROSINE PHOSPHORYLATED PROTEINS | NCE |
| 2018 | R33 | CA222344 | RFA-CA-17-011 | SALIPANTE, STEPHEN J | UNIVERSITY OF WASHINGTON | Advanced development and validation of genome-scale molecular diagnostics for microsatelliteinstability using targeted molecular counting methods | NCE |
| 2018 | R21 | CA214239 | RFA-CA-17-010 | VAN DEVENTER, JAMES ALLEN | TUFTS UNIVERSITY MEDFORD | Discovering hybrid inhibitors for tumor microenvironment disruption | NCE |
| 2018 | R21 | CA223715 | RFA-CA-17-010 | SHI, TUJIN | BATTELLE PACIFIC NORTHWEST LABORATORIES | An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells | Active |
| 2018 | R33 | CA223904 | RFA-CA-17-011 | CIMA, MICHAEL J | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Advanced development and validation of microdevices for high-throughput in situ drug sensitivity testing in tumors | NCE |
| 2018 | R33 | CA223908 | RFA-CA-17-011 | KONRY, TANIA TALI | NORTHEASTERN UNIVERSITY | Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platform | NCE |
| 2018 | R21 | CA223915 | RFA-CA-17-010 | KARGINOV, ANDREI V | UNIVERSITY OF ILLINOIS AT CHICAGO | Optogenetic tools for the dissection of oncogenic signaling mediated by kinases | NCE |
| 2018 | R33 | CA214310 | RFA-CA-17-013 | INCE, TAN A. | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE | Live Tumor Culture Core and Tissue Specific Culture (TSC) System for Human Cancers | Complete |
| 2018 | R21 | CA223836 | RFA-CA-17-010 | FIELDS, RYAN C | WASHINGTON UNIVERSITY | Advancing Cancer Biology, Diagnostics and Therapeutics Outside of the Patient: Creation of a Novel, Autologous, Ex Vivo, Vascularized Model of the Tumor Microenvironment | NCE |
| 2018 | R21 | CA223853 | RFA-CA-17-010 | ROBLES, FRANCISCO E | GEORGIA INSTITUTE OF TECHNOLOGY | Stimulated Raman scattering spectroscopic optical coherence tomography (SRS-SOCT) for label-free molecular imaging of brain tumor pathology | NCE |
| 2018 | R21 | CA223887 | RFA-CA-17-010 | SMITH, LLOYD M | UNIVERSITY OF WISCONSIN-MADISON | Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues | NCE |
| 2018 | R21 | CA223901 | RFA-CA-17-010 | BRENT, ROGER | FRED HUTCHINSON CANCER RESEARCH CENTER | Precision controllers of mammalian gene expression | Active |
| 2018 | R21 | CA225474 | RFA-CA-17-010 | MEHTA, ANAND S | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Glyco-typer: an antibody capture glycan imaging methodology | NCE |
| 2018 | R33 | CA225494 | RFA-CA-17-011 | LIU, YANG | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | High-throughput super-resolution imaging of chromatin structures at different epigenetic states | NCE |
| 2018 | R21 | CA225507 | RFA-CA-17-012 | PAULOVICH, AMANDA G | FRED HUTCHINSON CANCER RESEARCH CENTER | Validation of a disposable biospecimen collection system with integral refrigeration for preserving the phosphoproteome | NCE |