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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort ascending Award Type Project # RFA # PI/Project Leader Institution Title Status
2022 R33 CA258012 CA21-004 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic Control of Tumor Initiation and Tumor Progression in vivo Active
2022 R33 CA272321 CA21-004 WANG, TZA-HUEI JEFF JOHNS HOPKINS UNIVERSITY A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies Active
2022 R21 CA257864 CA21-003 BOYLE, ALAN P UNIVERSITY OF MICHIGAN AT ANN ARBOR High-throughput inverted reporter assay for characterization of silencers and enhancer blockers Complete
2022 R21 CA269091 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions Active
2022 R33 CA259451 CA21-004 NAEGLE, KRISTEN M UNIVERSITY OF VIRGINIA A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides Active
2022 R21 CA258008 CA21-003 SCARCELLI, GIULIANO UNIV OF MARYLAND, COLLEGE PARK Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential Complete
2022 R33 CA269094 CA21-004 MOELLERING, RAYMOND E UNIVERSITY OF CHICAGO Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues Active
2022 R21 CA272326 CA21-003 KELLY, RYAN T BRIGHAM YOUNG UNIVERSITY In-depth and label-free proteome profiling of hundreds of single cells per day Active
2022 R33 CA267221 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2022 R21 CA261775 CA21-003 LIN, QIAO COLUMBIA UNIV NEW YORK MORNINGSIDE A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies Active
2022 R21 CA261643 CA21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2022 R21 CA267222 CA21-003 LEE, HAKHO MASSACHUSETTS GENERAL HOSPITAL 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids Complete
2022 R21 CA269099 CA21-003 YAKOVLEV, VLADISLAV V TEXAS ENGINEERING EXPERIMENT STATION Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy Active
2022 R21 CA272345 CA21-003 KNOWLES, DAVID ARTHUR NEW YORK GENOME CENTER A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer Active
2022 R21 CA257980 CA21-003 BELCHER, ANGELA M MASSACHUSETTS INSTITUTE OF TECHNOLOGY A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage Complete
2022 R33 CA269100 CA21-004 CHIU, BRIAN C-H UNIVERSITY OF CHICAGO A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research Active
2022 R21 CA272351 CA21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2022 R33 CA267226 CA21-004 DRAKE, RICHARD R MEDICAL UNIVERSITY OF SOUTH CAROLINA Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids Complete
2022 R21 CA269103 CA21-003 BLAINEY, PAUL CLARK BROAD INSTITUTE, INC. Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout Active
2022 R33 CA272357 CA21-004 PAN, TAO UNIVERSITY OF CHICAGO Transfer RNA sequencing and application to cancer research and clinics Active
2022 R21 CA267260 CA21-003 ARMITAGE, BRUCE A CARNEGIE-MELLON UNIVERSITY Fluorescent gammaPNA Miniprobes for Imaging Telomeric RNA Complete
2022 R21 CA272014 CA21-003 SALIPANTE, STEPHEN J UNIVERSITY OF WASHINGTON Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations Active
2022 R33 CA267258 CA21-004 LEE, ABRAHAM P UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy Active
2022 R21 CA257816 CA21-003 COUNTER, CHRISTOPHER M DUKE UNIVERSITY Adapting K-MDS to detect KRAS-mutant ctDNA Active
2022 R21 CA272014 CA21-003 NABA, ALEXANDRA UNIVERSITY OF ILLINOIS AT CHICAGO Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix Active
2022 R21 CA267012 CA21-003 SNYDER, JOSHUA CLAIR DUKE UNIVERSITY Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color Active
2022 R33 CA261696 CA21-004 MERAJVER, SOFIA DIANA UNIVERSITY OF MICHIGAN AT ANN ARBOR Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence Active
2022 R21 CA267245 CA21-005 SHIBATA, DARRYL K UNIVERSITY OF SOUTHERN CALIFORNIA Photolithographic Tumor DNA Isolation Active
2022 R21 CA257942 CA21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2022 R33 CA269015 CA21-004 ADEY, ANDREW OREGON HEALTH & SCIENCE UNIVERSITY Accessible high-throughput single-cell genome sequencing Active
2022 R33 CA267219 CA21-004 LANDAU, DAN WEILL MEDICAL COLL OF CORNELL UNIV Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes Active
2022 R21 CA250999 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Aliquot-level visual indicators of biospecimen exposure to thawed conditions Complete
2021 R33 CA255893 RFA-CA-20-018 SEELIG, GEORG UNIVERSITY OF WASHINGTON Joint receptor and protein expression immunophenotyping through split-pool barcoding Active
2021 R33 CA256086 CA20-018 JIANG, NING JENNY UNIVERSITY OF PENNSYLVANIA A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells Complete
2021 R21 CA247647 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2021 R33 CA256102 RFA-CA-20-018 GREENBERG, JOEL DUKE UNIVERSITY Multimodality X-ray transmission and diffraction scanner for molecular analysis of cancer specimens Active
2021 R33 CA256112 CA20-018 WEI, WEI INSTITUTE FOR SYSTEMS BIOLOGY Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy Complete
2021 R21 CA250597 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2021 R33 CA257878 RFA-CA-20-018 HANSEN, ANDERS SEJR MASSACHUSETTS INSTITUTE OF TECHNOLOGY Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer Active
2021 R33 CA261726 CA20-018 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy Complete
2021 R21 CA251015 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2021 R33 CA258016 RFA-CA-20-018 LIU, XUEFENG OHIO STATE UNIVERSITY Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics Active
2021 R21 CA236686 CA20-017 FARIS, GREGORY W NUMENTUS TECHNOLOGIES INC. Decoding Individual Exosomes in Cancer Complete
2021 R21 CA255894 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2021 R44 CA261523 PAR-18-303 HUNG, PAUL JU-SUNG COMBINATI, INC. Digital Melt Curve Analysis Platform for Longitudinal Cancer Patient Monitoring Active
2021 R21 CA255979 CA20-017 DIDENKO, VLADIMIR V BAYLOR COLLEGE OF MEDICINE In situ assay imaging nuclear RNA exosome activity for cancer studies Complete
2021 R21 CA256081 RFA-CA-20-017 SWAGER, TIMOTHY M MASSACHUSETTS INSTITUTE OF TECHNOLOGY Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation Active
2021 R21 CA251043 CA20-017 HOSHIKA, SHUICHI FOUNDATION FOR APPLIED MOLECULAR EVOLUTN High Quality Proteins with Multiple Post Translational Modifications Complete
2021 R21 CA261737 CA20-017 HAINER, SARAH JANE UNIVERSITY OF PITTSBURGH AT PITTSBURGH Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN Complete
2021 R21 CA256082 RFA-CA-20-017 BAR-PELED, LIRON MASSACHUSETTS GENERAL HOSPITAL Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors Active

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