Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort descending
2019 R21 RFA-CA-18-004 ANDRES-MARTIN, LAURA NEW YORK STEM CELL FOUNDATION Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections Active
2018 R21 RFA-CA-17-010 ABBOTT, KAREN L UNIV OF ARKANSAS FOR MED SCIS Novel platform linking cancer-specific glycosylation with cell signaling outcomes Active
2017 R21 RFA-CA-16-001 NAEGLE, KRISTEN M WASHINGTON UNIVERSITY A MOLECULAR TOOLKIT FOR THE PRODUCTION OF TYROSINE PHOSPHORYLATED PROTEINS Active
2019 R33 RFA-CA-18-005 LEI, YUGUO UNIVERSITY OF NEBRASKA LINCOLN A Single Conical Tube Device for Precision CAR-T Cells Manufacturing Active
2019 R43 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations Active
2018 R21 RFA-CA-17-010 BRENT, ROGER FRED HUTCHINSON CANCER RESEARCH CENTER Precision controllers of mammalian gene expression Active
2020 R21 RFA-CA-19-019 HUR, SOOJUNG CLAIRE JOHNS HOPKINS UNIVERSITY Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy Active
2018 R21 RFA-CA-17-010 ENGLER, ADAM JEFFREY UNIVERSITY OF CALIFORNIA, SAN DIEGO Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells Active
2017 R21 RFA-CA-16-001 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Engineered regulation of tyrosine phosphatase activity in living cells Active
2020 R21 RFA-CA-19-019 REVZIN, ALEXANDER MAYO CLINIC ROCHESTER A microfluidic cell culture platform for personalizing pancreatic cancer therapies Active
2017 R21 RFA-CA-16-001 BROCK, AMY UNIVERSITY OF TEXAS, AUSTIN High resolution cell lineage tracking and isolation Active
2020 R21 RFA-CA-19-019 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics Active
2019 R21 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Active
2018 R21 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Active
2020 R21 RFA-CA-19-019 CICERONE, MARCUS T GEORGIA INSTITUTE OF TECHNOLOGY Label-Free Cell-Resolved Metabolomics for Tumor Microscopy Active
2019 R21 RFA-CA-18-002 HUANG, XIAOHUA UNIVERSITY OF CALIFORNIA, SAN DIEGO Technology for measuring telomere length of individual chromosomes of single cancer cells Active
2018 R21 RFA-CA-17-010 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic tools for the dissection of oncogenic signaling mediated by kinases Active
2020 R21 RFA-CA-19-019 SEELIG, GEORG UNIVERSITY OF WASHINGTON High-resolution spatial transcriptomics through light patterning Active
2019 R21 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2018 R21 RFA-CA-17-010 MAILLOUX, ADAM WILLIAM H. LEE MOFFITT CANCER CTR & RES INST Autohistomagnetic Isolation of Tumor-reactive T-cells Active
2017 R21 RFA-CA-16-001 WINDLE, BRAD E. VIRGINIA COMMONWEALTH UNIVERSITY The GOF Mutant p53 Beacon System Active
2020 R21 RFA-CA-19-019 MARTO, JARROD A DANA-FARBER CANCER INST Tools for DUB Drug Discovery Active
2019 R21 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2020 R33 RFA-CA-19-020 TAO, NONGJIAN ARIZONA STATE UNIVERSITY-TEMPE CAMPUS A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics Active
2019 R21 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Active
2018 R21 RFA-CA-17-010 ROBLES, FRANCISCO E GEORGIA INSTITUTE OF TECHNOLOGY Stimulated Raman scattering spectroscopic optical coherence tomography (SRS-SOCT) for label-free molecular imaging of brain tumor pathology Active
2020 R33 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies Active
2019 R21 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Active
2018 R21 RFA-CA-17-010 ROYZEN, MAKSIM STATE UNIVERSITY OF NEW YORK AT ALBANY Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies Active
2020 R33 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2019 R21 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2018 R21 RFA-CA-17-010 SCHIBEL, ANNA ELECTRONIC BIOSCIENCES, INC. Microsatellite Sequencing to Enable Cancer Genotyping Active
2020 R33 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2019 R21 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2018 R21 RFA-CA-17-010 SHI, TUJIN BATTELLE PACIFIC NORTHWEST LABORATORIES An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells Active
2018 R21 RFA-CA-17-010 SMITH, LLOYD M UNIVERSITY OF WISCONSIN-MADISON Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues Active
2017 R21 RFA-CA-16-001 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA A novel time-resolved fluorescence-based high-throughput screening technology for discovering allosteric kinase inhibitors Active
2020 R33 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2019 R21 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2018 R21 RFA-CA-17-010 VAN DEVENTER, JAMES ALLEN TUFTS UNIVERSITY MEDFORD Discovering hybrid inhibitors for tumor microenvironment disruption Active
2017 R21 RFA-CA-16-003 NECHAEV, SERGEI UNIVERSITY OF NORTH DAKOTA Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments. Active
2020 R33 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active
2019 R21 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2018 R33 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Active
2017 R21 RFA-CA-16-001 DICKINSON, BRYAN UNIVERSITY OF CHICAGO rePPI-i: A system for the rapid continuous evolution of protein-protein interaction inhibitors Active
2020 R21 RFA-CA-19-021 SEIBEL, ERIC J UNIVERSITY OF WASHINGTON Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy Active
2019 R21 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2018 R33 RFA-CA-17-011 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level Active
2020 R33 RFA-CA-19-022 HASHAM, MUNEER GULAMHUSEIN JACKSON LABORATORY Impact of Genetic Diversity on Human Xenograft Tumor Growth Active
2019 R21 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active

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