Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2022 | R21 | CA267222 | CA21-003 | LEE, HAKHO | MASSACHUSETTS GENERAL HOSPITAL | 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids | Active |
2022 | R33 | CA267221 | CA21-004 | NORMAN, THOMAS MAXWELL | SLOAN-KETTERING INST CAN RESEARCH | Systematic characterization of cancer variants using single-cell functional genomics | Active |
2022 | R21 | CA258008 | CA21-003 | SCARCELLI, GIULIANO | UNIV OF MARYLAND, COLLEGE PARK | Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential | Active |
2022 | R21 | CA257864 | CA21-003 | BOYLE, ALAN P | UNIVERSITY OF MICHIGAN AT ANN ARBOR | High-throughput inverted reporter assay for characterization of silencers and enhancer blockers | Active |
2022 | R21 | CA250999 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Aliquot-level visual indicators of biospecimen exposure to thawed conditions | Active |
2022 | R21 | CA267012 | CA21-003 | SNYDER, JOSHUA CLAIR | DUKE UNIVERSITY | Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color | Active |
2021 | R21 | CA263147 | CA20-017 | BHARGAVA, ROHIT | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN | Spectroscopy Assisted Laser Microdissection | Active |
2021 | R21 | CA256084 | CA20-017 | DI CARLO, DINO | UNIVERSITY OF CALIFORNIA LOS ANGELES | Lab on a particle technology for functional screening of therapeutic cells | Complete |
2021 | R21 | CA251027 | CA20-017 | SCHULMAN, REBECCA | JOHNS HOPKINS UNIVERSITY | Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) | Active |
2021 | R21 | CA256128 | CA20-017 | DEININGER, MICHAEL W | VERSITI WISCONSIN, INC. | A Bioluminescent Assay for Direct Measurement of Sirtuin Activity in Cancer Cells | NCE |
2021 | R21 | CA261737 | CA20-017 | HAINER, SARAH JANE | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN | Active |
2021 | R21 | CA261734 | CA20-019 | AKSAN, ALPTEKIN | UNIVERSITY OF MINNESOTA | Novel cryopreservation method for stabilization of manufactured therapeutic cells | Active |
2021 | R33 | CA256112 | CA20-018 | WEI, WEI | INSTITUTE FOR SYSTEMS BIOLOGY | Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy | Active |
2021 | R33 | CA256086 | CA20-018 | JIANG, NING JENNY | UNIVERSITY OF PENNSYLVANIA | A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells | Active |
2021 | R33 | CA261726 | CA20-018 | CHENG, JI-XIN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) | Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy | Active |
2021 | R21 | CA255979 | CA20-017 | DIDENKO, VLADIMIR V | BAYLOR COLLEGE OF MEDICINE | In situ assay imaging nuclear RNA exosome activity for cancer studies | Active |
2021 | R43 | CA261362 | PAR-18-303 | ALLEN, JEFFREY KEITH | TUMORGEN, INC. | Capture and Characterization of Highly Metastatic Cancer Cell Clusters in Transit from Lung Cancer Patient Whole Blood Specimens. | Active |
2021 | R33 | CA252158 | CA20-018 | ZENG, YONG | UNIVERSITY OF FLORIDA | Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles | Active |
2021 | R21 | CA236686 | CA20-017 | FARIS, GREGORY W | NUMENTUS TECHNOLOGIES INC. | Decoding Individual Exosomes in Cancer | NCE |
2021 | R21 | CA258013 | CA20-019 | NAUTIYAL, SHIVANI | PRIME GENOMICS, INC. | Device for Preservation of Cell Free RNA in Saliva | NCE |
2020 | R21 | CA240214 | RFA-CA-19-019 | CICERONE, MARCUS T | GEORGIA INSTITUTE OF TECHNOLOGY | Label-Free Cell-Resolved Metabolomics for Tumor Microscopy | Complete |
2020 | R33 | CA240181 | RFA-CA-19-020 | COOKS, ROBERT GRAHAM | PURDUE UNIVERSITY | Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies | Complete |
2020 | R33 | CA240191 | RFA-CA-19-020 | RECHT, MICHAEL | PALO ALTO RESEARCH CENTER | High-Throughput Screening Platform for Cancer Drug Discovery | Active |
2020 | R21 | CA247671 | RFA-CA-19-019 | MARTO, JARROD A | DANA-FARBER CANCER INST | Tools for DUB Drug Discovery | Complete |
2020 | R33 | CA247669 | RFA-CA-19-022 | HASHAM, MUNEER GULAMHUSEIN | JACKSON LABORATORY | Impact of Genetic Diversity on Human Xenograft Tumor Growth | Complete |
2020 | R44 | CA247353 | PAR-18-303 | FRIEDA, KIRSTEN | SPATIAL GENOMICS, INC. | Spatial and single cell analysis of tumor microenvironment by seqFISH+ | Complete |
2020 | R33 | CA246711 | RFA-CA-19-020 | FAN, RONG | YALE UNIVERSITY | High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer | Complete |
2020 | R21 | CA236653 | RFA-CA-19-019 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics | NCE |
2020 | R33 | CA246455 | RFA-CA-19-020 | CHEN, FEI | BROAD INSTITUTE, INC. | Clinical implementations of spatial transcriptomics in tumors | Complete |
2020 | R21 | CA229024 | RFA-CA-19-019 | HUR, SOOJUNG CLAIRE | JOHNS HOPKINS UNIVERSITY | Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy | Complete |
2020 | R33 | CA246363 | RFA-CA-19-020 | LEVINSON, NICHOLAS MARK | UNIVERSITY OF MINNESOTA | Time-resolved FRET-based allostery sensors for any protein kinase drug target | NCE |
2020 | R21 | CA246359 | RFA-CA-19-021 | SEIBEL, ERIC J | UNIVERSITY OF WASHINGTON | Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy | Complete |
2020 | R21 | CA246358 | RFA-CA-19-019 | SEELIG, GEORG | UNIVERSITY OF WASHINGTON | High-resolution spatial transcriptomics through light patterning | Complete |
2020 | R21 | CA236612 | RFA-CA-19-019 | REVZIN, ALEXANDER | MAYO CLINIC ROCHESTER | A microfluidic cell culture platform for personalizing pancreatic cancer therapies | NCE |
2019 | R33 | CA235319 | RFA-CA-18-003 | YANG, JENNY J. | GEORGIA STATE UNIVERSITY | Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment | Complete |
2019 | R33 | CA229068 | RFA-CA-18-003 | SCHIAVINATO EBERLIN, LIVIA | UNIVERSITY OF TEXAS, AUSTIN | Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation | Complete |
2019 | R21 | CA240580 | RFA-CA-18-002 | MONTAGNA, CRISTINA | ALBERT EINSTEIN COLLEGE OF MEDICINE | Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions | Complete |
2019 | R33 | CA235597 | RFA-CA-18-003 | SOPER, STEVEN ALLAN | UNIVERSITY OF KANSAS LAWRENCE | Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia | Complete |
2019 | R21 | CA240219 | RFA-CA-18-004 | ANDRES-MARTIN, LAURA | NEW YORK STEM CELL FOUNDATION | Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections | Complete |
2019 | R33 | CA240201 | RFA-CA-18-003 | VAN DAM, ROBERT MICHAEL | UNIVERSITY OF CALIFORNIA LOS ANGELES | Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research | Complete |
2019 | R21 | CA240199 | RFA-CA-18-002 | O'NEILL, RACHEL | UNIVERSITY OF CONNECTICUT STORRS | Development and Utilization of Splice-specific Antibodies | Complete |
2019 | R33 | CA235302 | RFA-CA-18-003 | DE VLAMINCK, IWIJN | CORNELL UNIVERSITY | Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer | Complete |
2019 | R21 | CA217662 | RFA-CA-18-002 | IM, HYUNGSOON | MASSACHUSETTS GENERAL HOSPITAL | Nano-plasmonic technology for high-throughput single exosome analyses | Complete |
2019 | R21 | CA240162 | RFA-CA-18-002 | KEUNG, ALBERT | NORTH CAROLINA STATE UNIVERSITY RALEIGH | Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening | Complete |
2019 | R21 | CA240148 | RFA-CA-18-002 | ANGEL, PEGGY M | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins | Complete |
2019 | R43 | CA239967 | PAR-18-303 | BROWN, MARK T | CLAREMONT BIOSOLUTIONS, LLC | Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis | Complete |
2019 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations | Complete |
2019 | R21 | CA236690 | RFA-CA-18-002 | KIM, HYUN JUNG | UNIVERSITY OF TEXAS, AUSTIN | A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk | Complete |
2019 | R33 | CA236687 | RFA-CA-18-003 | BREUNIG, JOSHUA JOHN | CEDARS-SINAI MEDICAL CENTER | GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models | Complete |
2019 | R21 | CA236685 | RFA-CA-18-002 | MANALIS, SCOTT R | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Building microenvironment-containing organoids from patient samples with single-cell precision | Complete |