Advancing Cancer Biology, Diagnostics and Therapeutics Outside of the Patient: Creation of a Novel, Autologous, Ex Vivo, Vascularized Model of the Tumor Microenvironment


Year of Award:
2018
Award Type:
R21
Project Number:
1R21CA223836-01
RFA Number:
RFA-CA-17-010
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
FIELDS, RYAN C
Other PI or Project Leader:
N/A
Institution:
WASHINGTON UNIVERSITY
The overall goal of this multi-disciplinary proposal is to create a novel, high-throughput, autologous, ex vivomodel system that recapitulates cancer biology, immuno-biology, vasculature formation, and multiple aspects ofthe tumor microenvironment (TME).