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Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments.


Year of Award:
2017
Status:
NCE
Award Type:
R21
Project Number:
CA217751
RFA Number:
RFA-CA-16-003
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
NECHAEV, SERGEI
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF NORTH DAKOTA

Global RNA sequencing technologies have revolutionized exploration of gene regulation in health and disease.However, RNA as a molecule is highly susceptible to degradation. As a result, RNA-sequencing, which hasbecome routine in basic research, does not w