Year of Award:
2017
Status:
Complete
Award Type:
R33
Project Number:
CA214176
RFA Number:
RFA-CA-16-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
LU, CHANG
Other PI or Project Leader:
N/A
Institution:
VIRGINIA POLYTECHNIC INST AND ST UNIV
External Link:
https://projectreporter.nih.gov/project_info_description.cfm?aid=9277756
Aberrant patterns in the epigenomic landscape have been closely associated with cancer.Deregulation of histone modifications silences tumor-suppressor genes, triggers geneticchanges via aberrant DNA repair/replication, and contributes to tumor heterogenei