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High-efficiency microfluidic-assisted single-cell DNA methylome sequencing


Year of Award:
2017
Status:
NCE
Award Type:
R21
Project Number:
CA212495
RFA Number:
RFA-CA-16-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
EASWARAN, HARIHARAN
Other PI or Project Leader:
PISANIC II, THOMAS RUSSELL
Institution:
JOHNS HOPKINS UNIVERSITY

The advancement of cancer epigenetics relies on highly efficient methods to detect DNA methylation. Ourgoal in this project is to devise a novel methodology for high-efficiency and high-throughput DNA methylationprofiling by whole genome bisulfite sequenc