VALIDATION AND ADVANCED DEVELOPMENT OF GLYCAN NODE ANALYSIS IN LUNG CANCER RESEARCH


Year of Award:
2015
Award Type:
R33
Project Number:
CA191110
RFA Number:
RFA-CA-14-004
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
BORGES, CHAD R
Other PI or Project Leader:
N/A
Institution:
ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
Glycotransferases are sugar polymer-building enzymes that build glycans in a non-template driven fashion. Aberrant glycotransferase activity creates abnormal sugar polymers (glycans) which are a hallmark of essentially every known cancer. Abnormal glycans