SINGLE CELL TECHNOLOGIES FOR RAPID DETECTION OF TUMOR HETEROGENEITY


Year of Award:
2015
Award Type:
R21
Project Number:
CA196460
RFA Number:
RFA-CA-14-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ANDERSON, KAREN SUE
Other PI or Project Leader:
BLATTMAN, JOSEPH N
Institution:
ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
Currently, there are few methods available to analyze the evolution of tumor heterogeneity; micro-dissection of tumors only provides information on major species of malignant cells but is unable to detect rare therapy-resistant subclones that have the pot