RESCUING NUCLEIC ACIDS FROM FORMALIN DAMAGE IN CANCER SPECIMENS


Year of Award:
2015
Award Type:
R43
Project Number:
CA199142
RFA Number:
PAR-13-327
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ORBAI, LUCIAN
Other PI or Project Leader:
ALIZADEH, ARASH ASH;KOOL, ERIC T.
Institution:
CELL DATA SCIENCES, INC.
Our proposed research is aimed at developing catalytic molecules and methods that greatly improve the recovery of biomolecular information from formalin-fixed tissue specimens. Formalin (formaldehyde) treatment of tissue is universally used in preparation