AN INTEGRATED IMAGING TOOL FOR PROBING EGFR SUBCELLULAR TRAFFICKING IN REAL TIME


Year of Award:
2015
Award Type:
R21
Project Number:
CA193038
RFA Number:
RFA-CA-14-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
YEH, HSIN-CHIH
Other PI or Project Leader:
DUNN, ANDREW K
Institution:
UNIVERSITY OF TEXAS, AUSTIN
In this work we propose to advance the state of the art in two-photon, three-dimensional molecular tracking and create a unique microscopy system to explore open questions in subcellular trafficking and spatial distribution of receptor tyrosine kinases (R