A NOVEL SINGLE-MOLECULE TELOMERE CHARACTERIZATION TECHNOLOGY FOR ANALYZING CANCER


Year of Award:
2014
Award Type:
R21
Project Number:
CA177395
RFA Number:
RFA-CA-13-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
RIETHMAN, HAROLD
Other PI or Project Leader:
XIAO, MING
Institution:
WISTAR INSTITUTE
Single-telomere-specific (TTAGGG)n tract lengths and instabilities cannot be measured globally using current methods; the ability to do so would be a major, transformative addition to the arsenal of tools for analyzing critical telomere loss an telomere e