Year of Award:
Molecular & Cellular Analysis Technologies
Other PI or Project Leader:
HOWELL, STEPHEN B
UNIVERSITY OF CALIFORNIA SAN DIEGO
DNA adducts are the hallmark and most common form of DNA damage in the cell. They result from environmental carcinogen exposure (such as UV) or during chemotherapy using DNA modifying agents like cisplatin (cDDP) or alkylators such as chlorambucil (CLB).