Error message

  • Deprecated function: Optional parameter $feed_nid declared before required parameter $context is implicitly treated as a required parameter in include_once() (line 1439 of /local/drupal/imat/includes/bootstrap.inc).
  • Deprecated function: Optional parameter $input declared before required parameter $form_state is implicitly treated as a required parameter in require_once() (line 12 of /local/drupal/imat/sites/all/modules/media/media.module).
×

IN VIVO DETECTION AND GENOME-WIDE LOCATION ANALYSIS OF DNA-ADDUCTS


Year of Award:
2013
Status:
Complete
Award Type:
R21
Project Number:
CA177519
RFA Number:
RFA-CA-12-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
HARISMENDY, OLIVIER
Other PI or Project Leader:
HOWELL, STEPHEN B
Institution:
UNIVERSITY OF CALIFORNIA SAN DIEGO
DNA adducts are the hallmark and most common form of DNA damage in the cell. They result from environmental carcinogen exposure (such as UV) or during chemotherapy using DNA modifying agents like cisplatin (cDDP) or alkylators such as chlorambucil (CLB).