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MICROFLUIDIC 3D ASSAYS FOR METASTATIC CANCER


Year of Award:
2013
Status:
Complete
Award Type:
R33
Project Number:
CA174550
RFA Number:
RFA-CA-12-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
KAMM, ROGER D.
Other PI or Project Leader:
N/A
Institution:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Migration from the primary tumor and through extra-cellular matrix (ECM), intravasation across a cellular barrier, and extravasation and recolonization in a remote site comprise the critical steps of cancer metastasis. Physiologically relevant and well-co