USE OF NANOGELS TO TARGET DELIVERY OF SIRNA TO CANCER CELLS IN MICE


Year of Award:
2011
Award Type:
R21
Project Number:
CA155479
RFA Number:
RFA-CA-10-005
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MCDONALD, JOHN F
Other PI or Project Leader:
N/A
Institution:
GEORGIA INSTITUTE OF TECHNOLOGY
Ovarian cancer is the leading cause of death from gynecologic cancer. Despite high initial tumor response rates of 80% to surgical debulking and chemotherapy, most women with advanced ovarian cancer will eventually develop drug-resistant disease. Because