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SENTINEL POL II RNAS FOR MEASURING RNA INTEGRITY IN BIOSPECIMENS


Year of Award:
2011
Status:
Complete
Award Type:
R21
Project Number:
CA148068
RFA Number:
RFA-CA-10-001
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
HAGEDORN, CURT H.
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF UTAH
The presence and quantity of specific RNA polymerase (Pol) II transcripts in biospecimens, that reflect gene expression patterns, are increasingly being used as biomarkers to make major patient care decisions (e.g., MammaPrintTM, array assay for 70 mRNAs)