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PLATFORM FOR HIGH-THROUGHPUT ANALYSIS OF PROTEIN ADDUCTS FOR CARCINOGEN EXPOSURE


Year of Award:
2011
Status:
Complete
Award Type:
R21
Project Number:
CA140036
RFA Number:
RFA-CA-10-005
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
DECAPRIO, ANTHONY P
Other PI or Project Leader:
BERMUDEZ, HARRY ;ROTELLO, VINCENT M.
Institution:
FLORIDA INTERNATIONAL UNIVERSITY
The long-term goal of this project is to develop a high-throughput technology that can characterize covalent protein and DNA modifications ('adducts') induced by reactive carcinogens on a global basis with high sensitivity and specificity. Virtually all c