METHODS OF SYSTEMATIC MICRORNA TARGET VALIDATION AND IDENTIFICATION


Year of Award:
2011
Award Type:
R21
Project Number:
CA138333
RFA Number:
RFA-CA-10-005
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MO, YIN-YUAN
Other PI or Project Leader:
N/A
Institution:
SOUTHERN ILLINOIS UNIVERSITY SCH OF MED
It is well known that microRNAs could play a fundamental role in regulation of diverse cellular functions. As key gene regulators, microRNAs work through a posttranscriptional repression mechanism. Increasing evidence indicates that deregulation of microR