ENHANCED FORMALIN FIXATION TO IMPROVE TESTS ON SOLID TISSUES


Year of Award:
2011
Status:
Complete
Award Type:
R21
Project Number:
CA155543
RFA Number:
RFA-CA-10-001
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
GULLEY, MARGARET L
Other PI or Project Leader:
N/A
Institution:
UNIV OF NORTH CAROLINA CHAPEL HILL
Standard pathology practice relies on automated processing of tissues fixed in 10% neutral buffered formalin followed by staining protocols that were optimized over the past century for microscopic visualization. In the last two decades, molecular assays