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TISSUE-SPECIFIC MUTAGENESIS IN RAT AS AN IN VIVO TOOL FOR COLON CANCER GENE DISCO


Year of Award:
2009
Status:
Complete
Award Type:
R43
Project Number:
CA138336
RFA Number:
RFA-CA-08-011
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
RUIZ, JOSEPH C
Other PI or Project Leader:
N/A
Institution:
TRANSPOSAGEN BIOPHARMACEUTICALS, INC.
The outcome of this SBIR application will be a rat model of colorectal cancer (CRC), which can be used to discover new targets for colon cancer therapy. CRC rats will be produced using Transposagen's novel technology for introducing somatic mutations in r