NEW FLUORESCENT CASPASE DETECTION PROBES TO LABEL APOPTOTIC TUMOR CELLS IN VIVO


Year of Award:
2009
Award Type:
R44
Project Number:
CA134310
RFA Number:
RFA-CA-07-041
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
LEE, BRIAN W
Other PI or Project Leader:
JOHNSON, GARY LEON
Institution:
IMMUNOCHEMISTRY TECHNOLOGIES, LLC
The identification of apoptotic events has important applications for detecting cell death induced by disease, injury, therapeutics, or normal tissue development and differentiation. Activation of the intracellular caspase cascade is a well understood mec