ANTIBODY-BASED DETECTION OF TRANSLOCATIONS IN PEDIATRIC CANCER


Year of Award:
2009
Award Type:
R21
Project Number:
CA138295
RFA Number:
RFA-CA-08-006
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
LESSNICK, STEPHEN L.
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF UTAH
Many cancers are associated with recurrent abnormalities of chromosome structure. One abnormality, a chromosomal translocation, occurs when portions of two normal chromosomes are exchanged. In the cancer setting, translocations may change the expression o