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TIME-RESOLVED FLUOROMETRIC METHOD FOR ASSAY OF MULTIPLE BIOMARKERS


Year of Award:
2008
Status:
Complete
Award Type:
R21
Project Number:
CA134386
RFA Number:
RFA-CA-07-033
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SZMACINSKI, HENRYK
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF MARYLAND BALTIMORE
In this application we propose the development of technology with potential of at least 100-fold improved sensitivity over current fluorometric methods. Specifically we integrate a metal enhanced fluorescence (MEF) with time-resolved detection technique t