APPLICATION OF TECHNOLOGIES FOR INTERACTOME NETWORK ANALYSES OF CANCER MUTATIONS


Year of Award:
2008
Award Type:
R33
Project Number:
CA132073
RFA Number:
RFA-CA-07-036
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
VIDAL, MARC
Other PI or Project Leader:
N/A
Institution:
DANA-FARBER CANCER INST
The molecular mechanisms underlying cancer have been mainly studied one or a few 'cancer genes' at-a-time. However, it is thought that combinations of mutated or aberrantly expressed tumor suppressor- and oncogenes may be responsible for advancing cells t