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IN VIVO IMAGING OF MATRIX METALLOPROTEASE


Year of Award:
2000
Status:
Complete
Award Type:
R21
Project Number:
CA088365
RFA Number:
PAR-99-100
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
TUNG, CHING-HSUAN
Other PI or Project Leader:
N/A
Institution:
MASSACHUSETTS GENERAL HOSPITAL
The ability to detect specific enzyme activities in vivo would have far reaching applications in diagnosing, characterizing and assessing novel treatments of cancer. We have recently developed and validated imaging probes for the in vivo sensing of speci