COMPARATIVE HYBRIDIZATION OF AP PCR ARRAYS


Year of Award:
2000
Status:
Complete
Award Type:
R21
Project Number:
CA083241
RFA Number:
PAR-99-100
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MALKHOSYAN, SERGEI R
Other PI or Project Leader:
N/A
Institution:
BURNHAM INSTITUTE FOR MEDICAL RESEARCH
We applied an unbiased DNA fingerprinting technique, the Arbitrarily-Primed PCR (AP-PCR) to study tumor- specific genetic changes. AP-PCR is a PCR-based DNA fingerprinting method, which uses a single oligonucleotide primer of arbitrary sequence, and gene