How do I know if my project is responsive?

Read through the Responsive and Non-Responsive Criteria that is described in every RFA. The most common reasons an application is found non-responsive are because (1) the project is pursuing hypothesis-driven research rather than developing a technology, (2) the application does not contain quantitative performance measures, or (3) the project is too far along (i.e. the technology is already developed and there is no question of feasibility) for the R21/R61 grant mechanism. If you have any questions about whether your proposal is responsive, please reach out to the IMAT program team and we would be happy to advise you.