The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues


Year of Award:
2017
Status:
Complete
Award Type:
R33
Project Number:
CA206939
RFA Number:
RFA-CA-16-004
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
PATTENDEN, SAMANTHA GAIL
Other PI or Project Leader:
DAVIS, IAN J;DAYTON, PAUL A
Institution:
UNIV OF NORTH CAROLINA CHAPEL HILL

Formalin-fixed paraffin embedded (FFPE) patient biopsy samples represent an important source of tumortissue for cancer research. FFPE samples can be used to extract DNA for analyzing tumor-specific genemutations and for cancer diagnostics. There is consid