A Vascularized, In Vitro, Organotropic Metastasis Model to Generate Dormant Micrometastases


Year of Award:
2017
Status:
Complete
Award Type:
R21
Project Number:
CA214299
RFA Number:
RFA-CA-16-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SLATER, JOHN HUNDLEY
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF DELAWARE

Metastasis is responsible for 90% of cancer associated mortality indicating the need for new therapies targetedspecifically toward preventing and/or eliminating metastasis. Cells originating from breast tumors display distinctorganotropic metastasis patte