Tag-ChIP-MS for analysis of chromatin-level regulation of DNA repair


Year of Award:
2017
Status:
Complete
Award Type:
R21
Project Number:
CA213247
RFA Number:
RFA-CA-16-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
KRON, STEPHEN J.
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CHICAGO

Recent progress on proteomic analysis of chromatin has led to significant discoveries but has alsorevealed limitations of current ChIP-MS strategies. In particular, comparing results among experiments andlaboratories is challenging. Here, we will leverage