ONLINE RAMAN DIAGNOSTICS OF ONCOMETABOLITES


Year of Award:
2016
Award Type:
R33
Project Number:
1R33CA206922-01
RFA Number:
RFA-CA-15-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SCHULTZ, ZACHARY
Other PI or Project Leader:
Not Applicable
Institution:
UNIVERSITY OF NOTRE DAME
To optimize a new platform for detecting metabolites based on scattering-enhanced Raman spectroscopy using the PI?s recently developed ?sheath-flow? device for introducing samples to the detection area. Importantly, this approach is meant to serve as an alternative to those involving the use of mass spectrometry, which is the predominant tool for studying metabolites, and suffers from a number of important shortcomings for studying this class of analytes.