Year of Award:
Molecular & Cellular Analysis Technologies
Other PI or Project Leader:
UNIVERSITY OF NOTRE DAME
To optimize a new platform for detecting metabolites based on scattering-enhanced Raman spectroscopy using the PI?s recently developed ?sheath-flow? device for introducing samples to the detection area. Importantly, this approach is meant to serve as an alternative to those involving the use of mass spectrometry, which is the predominant tool for studying metabolites, and suffers from a number of important shortcomings for studying this class of analytes.