Year of Award:
Molecular & Cellular Analysis Technologies
SEGAL, DAVID J
Other PI or Project Leader:
UNIVERSITY OF CALIFORNIA AT DAVIS
To modify the dCas9 enzyme of the CRISPR system to create a better tool for site specific editing of epigenetic marks. This innovative design involves a unique combination of functional elements yielding a system addressing a variety of shortcomings with regards to existing epigenetic editing approaches.