ELECTROCHEMICAL SYNTHESIS OF RADIOPHARMACEUTICALS


Year of Award:
2016
Award Type:
R21
Project Number:
1R21CA186842-01A1
RFA Number:
RFA-CA-15-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SADEGHI , SAMAN
Other PI or Project Leader:
Not Applicable
Institution:
UNIVERSITY OF CALIFORNIA LOS ANGELES
To develop an electrochemical platform for synthesizing PET tracers with 18F-radiolabelled aromatic and heteroaromatic moieties via a small benchtop system that simplifies their production and makes such probes more accessible to the broader research community. The clinical potential, if successful, is improved availability of known and novel PET probes, presently not accessible due to difficulties in synthesis with conventional approaches, which will enhance disease diagnosis and management.