SINGLE CELL CYTOKINE ANALYSIS OF CIRCULATING MALIGNANT HEMATOPOIETIC CELLS


Year of Award:
2015
Award Type:
R33
Project Number:
CA196411
RFA Number:
RFA-CA-14-004
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
FAN, RONG
Other PI or Project Leader:
LEVINE, ROSS L
Institution:
YALE UNIVERSITY
Myeloproliferative malignancies are clonal blood diseases in which a dysregulated excessive or dysplastic production of blood cells driven by the gain-of-function mutations in the bone marrow hematopoietic stem/progenitor cells. While the common mutations