PHOTOREACTIVE HISTONE DEACETYLASE PROBES FOR CHROMATIN IMMUNOPRECIPITATION IN CAN


Year of Award:
2014
Award Type:
R21
Project Number:
CA183627
RFA Number:
RFA-CA-13-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
PETUKHOV, PAVEL A
Other PI or Project Leader:
FRASOR, JONNA
Institution:
UNIVERSITY OF ILLINOIS AT CHICAGO
Identification of the components of transcription complexes and the genes associated/regulated by them are at the heart of all modern discoveries. As key epigenetic players with essential biological functions, histone deacetylases (HDACs) are among the mo